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Descriptor English: Megestrol
Descriptor Spanish: Megestrol
Descriptor Portuguese: Megestrol
Descriptor French: Mégestrol
Entry term(s): 17-Hydroxy-6-methylpregna-3,6-diene-3,20-dione
Pregna-4,6-diene-3,20-dione, 17-hydroxy-6-methyl-
Tree number(s): D04.210.500.745.432.531
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D008535
Scope note: A progestational hormone used most commonly as the acetate ester. As the acetate, it is more potent than progesterone both as a progestagen and as an ovulation inhibitor. It has also been used in the palliative treatment of breast cancer.
Annotation: a synthetic progestational hormone
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Contraceptives, Oral, Synthetic
Antineoplastic Agents, Hormonal
Registry Number: EA6LD1M70M
CAS Type 1 Name: Pregna-4,6-diene-3,20-dione, 17-hydroxy-6-methyl-
Public MeSH Note: 72
History Note: 72(63)
DeCS ID: 8704
Unique ID: D008535
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1972/01/01
Date of Entry: 1999/01/01
Revision Date: 2019/07/08
Megestrol - Preferred
Concept UI M0013296
Scope note A progestational hormone used most commonly as the acetate ester. As the acetate, it is more potent than progesterone both as a progestagen and as an ovulation inhibitor. It has also been used in the palliative treatment of breast cancer.
Preferred term Megestrol
Entry term(s) 17-Hydroxy-6-methylpregna-3,6-diene-3,20-dione
Pregna-4,6-diene-3,20-dione, 17-hydroxy-6-methyl-



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