| Descriptor English: | Mixed Connective Tissue Disease | ||||||
| Descriptor Spanish: |
Enfermedad Mixta del Tejido Conjuntivo
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| Descriptor Portuguese: | Doença Mista do Tecido Conjuntivo | ||||||
| Descriptor French: | Connectivite mixte | ||||||
| Entry term(s): |
Connective Tissue Disease, Mixed MCTD Sharp Syndrome Syndrome, Sharp |
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| Tree number(s): |
C17.300.540 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D008947 | ||||||
| Scope note: | A syndrome with overlapping clinical features of systemic lupus erythematosus, scleroderma, polymyositis, and Raynaud's phenomenon. The disease is differentially characterized by high serum titers of antibodies to ribonuclease-sensitive extractable (saline soluble) nuclear antigen and a "speckled" epidermal nuclear staining pattern on direct immunofluorescence. |
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| Annotation: | a specific disease entity; do not confuse with CONNECTIVE TISSUE DISEASES |
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| Allowable Qualifiers: |
BL blood CF cerebrospinal fluid CI chemically induced CL classification CN congenital CO complications DG diagnostic imaging DH diet therapy DI diagnosis DT drug therapy EC economics EH ethnology EM embryology EN enzymology EP epidemiology ET etiology GE genetics HI history IM immunology ME metabolism MI microbiology MO mortality NU nursing PA pathology PC prevention & control PP physiopathology PS parasitology PX psychology RH rehabilitation RT radiotherapy SU surgery TH therapy UR urine VE veterinary VI virology |
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| Previous Indexing: |
Collagen Diseases (1972-1978) Lupus Erythematosus, Systemic (1972-1978) Scleroderma, Systemic (1972-1978) |
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| Public MeSH Note: | 79 |
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| History Note: | 79 |
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| Entry Version: | MIXED CONNECTIVE TISSUE DIS |
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| DeCS ID: | 9137 | ||||||
| Unique ID: | D008947 | ||||||
| NLM Classification: | WD 375 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1979/01/01 | ||||||
| Date of Entry: | 1978/05/15 | ||||||
| Revision Date: | 2013/07/09 |
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Mixed Connective Tissue Disease
- Preferred
| Concept UI |
M0013961 |
| Scope note | A syndrome with overlapping clinical features of systemic lupus erythematosus, scleroderma, polymyositis, and Raynaud's phenomenon. The disease is differentially characterized by high serum titers of antibodies to ribonuclease-sensitive extractable (saline soluble) nuclear antigen and a "speckled" epidermal nuclear staining pattern on direct immunofluorescence. |
| Preferred term | Mixed Connective Tissue Disease |
| Entry term(s) |
Connective Tissue Disease, Mixed MCTD Sharp Syndrome Syndrome, Sharp |
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