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Descriptor English: Muscimol
Descriptor Spanish: Muscimol
Descriptor muscimol
Entry term(s) agarin
panterina
Scope note: Isoxazol neurotóxico aislado de la Amanita muscaria y A. phalloides, que también se obtiene mediante descarboxilación del ÁCIDO IBOTÉNICO. Es un potente agonista de los receptores GABA-A y se utiliza principalmente como herramienta experimental en estudios sobre animales y tejidos.
Descriptor Portuguese: Muscimol
Descriptor French: Muscimol
Entry term(s): 5-Aminométhyl-isoxazol-3-one
5-Aminométhylisoxazol-3-one
Agarine
Panthérine
Tree number(s): D03.383.129.462.470
D23.946.587.587
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D009118
Scope note: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
Allowable Qualifiers: AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine
Pharm Action: GABA-A Receptor Agonists
Registry Number: 2763-96-4
CAS Type 1 Name: 3(2H)-Isoxazolone, 5-(aminomethyl)-
Related: Récepteurs GABA-A MeSH
DeCS ID: 9308
Unique ID: D009118
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1986/01/01
Date of Entry: 1978/05/03
Revision Date: 2016/05/31
Muscimol - Preferred
Concept UI M0014231
Preferred term Muscimol
Entry term(s) 5-Aminométhyl-isoxazol-3-one
5-Aminométhylisoxazol-3-one
Agarine
Panthérine



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