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Descriptor English: Myelin Sheath
Descriptor Spanish: Vaina de Mielina
Descriptor vaina de mielina
Entry term(s) mielina
Scope note: Cubierta rica en lípidos que rodea a los AXONES tanto en el SISTEMA NERVIOSO CENTRAL como en el SISTEMA NERVIOSO PERIFÉRICO. La vaina de mielina es un aislante eléctrico que favorece una más rápida y energéticamente más eficiente conducción de los impulsos. La vaina está constituida por las membranas celulares de células gliales (CÉLULAS DE SCHWANN en los nervios periféricos y OLIGODENDROGLÍA en el sistema nervioso central). El deterioro de la vaina de mielina en las ENFERMEDADES DESMIELINIZANTES constituye una afección clínica grave.
Descriptor Portuguese: Bainha de Mielina
Descriptor French: Gaine de myéline
Entry term(s): Myéline
Tree number(s): A08.637.600.500
A08.637.800.500
A08.675.542.512.560
A08.800.800.690.500
A10.755.503
A11.284.149.165.600
A11.650.600.500
A11.650.800.500
A11.671.501.512.560
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D009186
Scope note: The lipid-rich sheath surrounding AXONS in both the CENTRAL NERVOUS SYSTEMS and PERIPHERAL NERVOUS SYSTEM. The myelin sheath is an electrical insulator and allows faster and more energetically efficient conduction of impulses. The sheath is formed by the cell membranes of glial cells (SCHWANN CELLS in the peripheral and OLIGODENDROGLIA in the central nervous system). Deterioration of the sheath in DEMYELINATING DISEASES is a serious clinical problem.
Annotation: note entry term MYELIN; do not confuse with MYELIN PROTEINS; myelination: index under MYELIN SHEATH / physiol
Allowable Qualifiers: CH composition chimique
CL classification
DE effets des médicaments et des substances chimiques
EN enzymologie
GE génétique
IM immunologie
ME métabolisme
MI microbiologie
PA anatomopathologie
PH physiologie
PS parasitologie
RE effets des radiations
TR transplantation
UL ultrastructure
VI virologie
DeCS ID: 9378
Unique ID: D009186
NLM Classification: WL 102.5
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2014/06/13
Gaine de myéline - Preferred
Concept UI M0014320
Preferred term Gaine de myéline
Myéline - Narrower
Concept UI M0014319
Preferred term Myéline



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