DeCS

Descriptor en español:

Somatostatina

Español de España

Descriptor	somatostatina
Término(s) alternativo(s)	hormona inhibidora de la liberación de somatotropina somatostatina 14 somatostatina cíclica
Nota de alcance:	Péptido de 14 aminoácidos conocido por su capacidad de inhibir la liberación de SOMATOTROPINA y al que también se conoce como factor inhibidor de la liberación de somatotropina. Se expresa en el sistema nervioso central y periférico, el intestino y otros órganos. SRIF también puede inhibir la liberación de TIROTROPINA, PROLACTINA, INSULINA y GLUCAGÓN además de actuar como neutrotransmisor y neuromodulador. En algunas especies, incluida la humana, existe otra forma de somatostatina, SRIF-28, con una extensión de 14 aminoácidos en el extremo N-terminal.

Descriptor en inglés:

Somatostatin

Descriptor en portugués:

Somatostatina

Descriptor en francés:

Somatostatine

Término(s) alternativo(s):

Cyclic Somatostatin
SRIH-14
Somatofalk
Somatostatin 14
Somatostatin, Cyclic
Somatostatin-14
Somatotropin Release Inhibiting Factor
Somatotropin Release Inhibiting Hormone
Somatotropin Release-Inhibiting Factor
Somatotropin Release-Inhibiting Hormone
Stilamin

Código(s) jeráquico(s):

D06.472.699.327.700.875
D06.472.699.587.780
D12.644.400.400.700.875
D12.644.548.365.700.875
D12.644.548.586.780
D12.776.631.650.405.700.875

Identificador Único RDF:

https://id.nlm.nih.gov/mesh/D013004

Nota de alcance:

A 14-amino acid peptide named for its ability to inhibit pituitary GROWTH HORMONE release, also called somatotropin release-inhibiting factor. It is expressed in the central and peripheral nervous systems, the gut, and other organs. SRIF can also inhibit the release of THYROID-STIMULATING HORMONE; PROLACTIN; INSULIN; and GLUCAGON besides acting as a neurotransmitter and neuromodulator. In a number of species including humans, there is an additional form of somatostatin, SRIF-28 with a 14-amino acid extension at the N-terminal.

Calificadores permitidos:

AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine

UI del concepto	M0020152
Nota de alcance	A 14-amino acid peptide named for its ability to inhibit pituitary GROWTH HORMONE release, also called somatotropin release-inhibiting factor. It is expressed in the central and peripheral nervous systems, the gut, and other organs. SRIF can also inhibit the release of THYROID-STIMULATING HORMONE; PROLACTIN; INSULIN; and GLUCAGON besides acting as a neurotransmitter and neuromodulator. In a number of species including humans, there is an additional form of somatostatin, SRIF-28 with a 14-amino acid extension at the N-terminal.
Término preferido	Somatostatin
Término(s) alternativo(s)	Cyclic Somatostatin SRIH-14 Somatostatin 14 Somatostatin, Cyclic Somatostatin-14 Somatotropin Release Inhibiting Factor Somatotropin Release Inhibiting Hormone Somatotropin Release-Inhibiting Factor Somatotropin Release-Inhibiting Hormone

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