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Descriptor en español: |
Transducción de Señal
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Descriptor en inglés: | Signal Transduction | ||||||
Descriptor en portugués: | Transdução de Sinais | ||||||
Descriptor en francés: | Transduction du signal | ||||||
Término(s) alternativo(s): |
Cell Signaling Pathway, Signal Pathway, Signal Transduction Pathways, Signal Pathways, Signal Transduction Receptor Mediated Signal Transduction Receptor-Mediated Signal Transduction Receptor-Mediated Signal Transductions Signal Pathway Signal Pathways Signal Transduction Pathway Signal Transduction Pathways Signal Transduction System Signal Transduction Systems Signal Transduction, Receptor-Mediated Signal Transductions Signal Transductions, Receptor-Mediated System, Signal Transduction Systems, Signal Transduction Transduction, Signal Transductions, Signal |
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Código(s) jeráquico(s): |
G02.111.820 G04.835 |
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Identificador Único RDF: | https://id.nlm.nih.gov/mesh/D015398 | ||||||
Nota de alcance: | The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway. |
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Calificadores permitidos: |
DE drug effects GE genetics IM immunology PH physiology RE radiation effects |
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Indexación anterior: |
Membrane Potentials (1977-1988) specific compounds/physiology (1977-1988) |
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Nota Pública de MeSH: | 89 |
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Nota de historia: | 89 |
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Vea también los descriptores: |
Ion Channels
MeSH | ||||||
Identificador de DeCS: | 23827 | ||||||
ID del Descriptor: | D015398 | ||||||
Clasificación de la NLM: | QU 375 | ||||||
Documentos indizados en la Biblioteca Virtual de Salud (BVS): | Haga clic aquí para acceder a los documentos de la BVS | ||||||
Fecha de establecimiento: | 01/01/1989 | ||||||
Fecha de entrada: | 06/06/1988 | ||||||
Fecha de revisión: | 05/07/2019 |
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PHENOMENA AND PROCESSES
Chemical Phenomena [G02]Chemical Phenomena -
PHENOMENA AND PROCESSES
Cell Physiological Phenomena [G04]Cell Physiological Phenomena
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Signal Transduction
- Concepto preferido
Signal Pathways
- Más estrecho
Signal Transduction Pathways
- Más estrecho
Receptor-Mediated Signal Transduction
- Más estrecho
UI del concepto |
M0023729 |
Nota de alcance | The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway. |
Término preferido | Signal Transduction |
Término(s) alternativo(s) |
Cell Signaling Signal Transduction System Signal Transduction Systems Signal Transductions System, Signal Transduction Systems, Signal Transduction Transduction, Signal Transductions, Signal |
UI del concepto |
M0023728 |
Término preferido | Signal Pathways |
Término(s) alternativo(s) |
Pathway, Signal Pathways, Signal Signal Pathway |
UI del concepto |
M0023730 |
Término preferido | Signal Transduction Pathways |
Término(s) alternativo(s) |
Pathway, Signal Transduction Pathways, Signal Transduction Signal Transduction Pathway |
UI del concepto |
M0023727 |
Término preferido | Receptor-Mediated Signal Transduction |
Término(s) alternativo(s) |
Receptor Mediated Signal Transduction Receptor-Mediated Signal Transductions Signal Transduction, Receptor-Mediated Signal Transductions, Receptor-Mediated |
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