Ha seleccionado la visión en Inglés
Descriptor en español: |
Regulación hacia Abajo
| ||||||
Descriptor en inglés: | Down-Regulation | ||||||
Descriptor en portugués: | Regulação para Baixo | ||||||
Descriptor en francés: | Régulation négative | ||||||
Término(s) alternativo(s): |
Down Regulation Down-Regulation (Physiology) Down-Regulation, Receptor Downregulation Receptor Down-Regulation |
||||||
Código(s) jeráquico(s): |
G02.111.240 G05.308.200 G07.690.773.937 |
||||||
Identificador Único RDF: | https://id.nlm.nih.gov/mesh/D015536 | ||||||
Nota de alcance: | A negative regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins. |
||||||
Calificadores permitidos: |
DE drug effects GE genetics IM immunology PH physiology RE radiation effects |
||||||
Nota Pública de MeSH: | 2002; see Down-Regulation (Physiology) 1990-2001 |
||||||
Nota de historia: | 2002 (1990) |
||||||
Vea también los descriptores: |
Feedback, Physiological
MeSH Up-Regulation MeSH | ||||||
Identificador de DeCS: | 24611 | ||||||
ID del Descriptor: | D015536 | ||||||
Documentos indizados en la Biblioteca Virtual de Salud (BVS): | Haga clic aquí para acceder a los documentos de la BVS | ||||||
Fecha de establecimiento: | 01/01/1990 | ||||||
Fecha de entrada: | 26/05/1989 | ||||||
Fecha de revisión: | 17/06/2016 |
-
-
PHENOMENA AND PROCESSES
Chemical Phenomena [G02]Chemical Phenomena -
PHENOMENA AND PROCESSES
Genetic Phenomena [G05]Genetic Phenomena -
PHENOMENA AND PROCESSES
Physiological Phenomena [G07]Physiological Phenomena
|
Down-Regulation
- Concepto preferido
Receptor Down-Regulation
- Más estrecho
UI del concepto |
M0023902 |
Nota de alcance | A negative regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins. |
Término preferido | Down-Regulation |
Término(s) alternativo(s) |
Down Regulation Down-Regulation (Physiology) Downregulation |
UI del concepto |
M0374370 |
Nota de alcance | A negative regulatory process that decreases ligand-receptor interactions. Reduction in receptor binding after ligand exposure can result from the internalization of ligand-receptor complex, an increase in receptor degradation, and/or a decrease in gene expression resulting in a decrease in receptor biosynthesis. |
Término preferido | Receptor Down-Regulation |
Término(s) alternativo(s) |
Down-Regulation, Receptor |
Queremos sus comentarios sobre el nuevo sitio web de DeCS / MeSH
Lo invitamos a completar una encuesta que no tomará más de 3 minutos.
Ir a la encuesta