DeCS

Descriptor en español:

Inmunotoxinas

Español de España

Descriptor	inmunotoxinas
Término(s) alternativo(s)	afinotoxina afinotoxinas conjugado anticuerpo monoclonal-toxina conjugado anticuerpo-toxina conjugado citotoxina-anticuerpo conjugado de toxina-anticuerpo conjugados anticuerpo-toxina conjugados citotoxina-anticuerpo conjugados de toxinas conjugados toxina-anticuerpo híbrido anticuerpo-toxina híbrido toxina-anticuerpo híbridos de anticuerpo-toxina híbridos toxina-anticuerpo toxina dirigida toxinas diana transportadores de toxinas
Nota de alcance:	Conjugados semisintéticos de diversas moléculas tóxicas, que incluyen ISÓTOPOS RADIOACTIVOS y TOXINAS de bacterias o de plantas, con sustancias inmunitarias específicas tales como INMUNOGLOBULINAS, ANTICUERPOS MONOCLONALES y ANTÍGENOS. La sustancia inmunitaria antitumoral o antivírica transporta la toxina hasta el tumor o célula infectada en donde la toxina ejerce su efecto tóxico.

Descriptor en inglés:

Immunotoxins

Descriptor en portugués:

Imunotoxinas

Descriptor en francés:

Immunotoxines

Término(s) alternativo(s):

Affinotoxin
Affinotoxins
Antibody Toxin Conjugate
Antibody Toxin Conjugates
Antibody Toxin Hybrid
Antibody Toxin Hybrids
Antibody-Toxin Conjugate
Antibody-Toxin Conjugate, Monoclonal
Antibody-Toxin Conjugates
Antibody-Toxin Conjugates, Monoclonal
Antibody-Toxin Hybrid
Antibody-Toxin Hybrids
Carrier, Toxin
Carriers, Toxin
Chimeric Toxin
Chimeric Toxins
Conjugate, Antibody-Toxin
Conjugate, Cytotoxin-Antibody
Conjugate, Monoclonal Antibody-Toxin
Conjugate, Toxin
Conjugate, Toxin-Antibody
Conjugates, Antibody-Toxin
Conjugates, Cytotoxin-Antibody
Conjugates, Monoclonal Antibody-Toxin
Conjugates, Toxin
Conjugates, Toxin-Antibody
Cytotoxin Antibody Conjugate
Cytotoxin Antibody Conjugates
Cytotoxin-Antibody Conjugate
Cytotoxin-Antibody Conjugates
Hybrid, Antibody-Toxin
Hybrid, Toxin-Antibody
Hybrids, Antibody-Toxin
Hybrids, Toxin-Antibody
Immunotoxin
Monoclonal Antibody Toxin Conjugate
Monoclonal Antibody Toxin Conjugates
Monoclonal Antibody-Toxin Conjugate
Monoclonal Antibody-Toxin Conjugates
Targeted Toxin
Targeted Toxins
Toxin Antibody Conjugate
Toxin Antibody Conjugates
Toxin Antibody Hybrid
Toxin Antibody Hybrids
Toxin Carrier
Toxin Carriers
Toxin Conjugate
Toxin Conjugates
Toxin, Chimeric
Toxin, Targeted
Toxin-Antibody Conjugate
Toxin-Antibody Conjugates
Toxin-Antibody Hybrid
Toxin-Antibody Hybrids
Toxins, Chimeric
Toxins, Targeted

Código(s) jeráquico(s):

D12.776.124.790.651.114.580.450
D12.776.377.715.548.114.580.450
D27.505.696.477.266.500
D27.888.569.279

Identificador Único RDF:

https://id.nlm.nih.gov/mesh/D000922

Nota de alcance:

Semisynthetic conjugates of various toxic molecules, including RADIOACTIVE ISOTOPES and bacterial or plant toxins, with specific immune substances such as IMMUNOGLOBULINS; MONOCLONAL ANTIBODIES; and ANTIGENS. The antitumor or antiviral immune substance carries the toxin to the tumor or infected cell where the toxin exerts its poisonous effect.

Nota de indización:

coordinate IM with specific toxin (IM) + specific immune substance (NIM)

Calificadores permitidos:

AD administration & dosage
AE adverse effects
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
DE drug effects
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine

UI del concepto	M0001373
Nota de alcance	Semisynthetic conjugates of various toxic molecules, including RADIOACTIVE ISOTOPES and bacterial or plant toxins, with specific immune substances such as IMMUNOGLOBULINS; MONOCLONAL ANTIBODIES; and ANTIGENS. The antitumor or antiviral immune substance carries the toxin to the tumor or infected cell where the toxin exerts its poisonous effect.
Término preferido	Immunotoxins
Término(s) alternativo(s)	Affinotoxin Affinotoxins Antibody Toxin Conjugate Antibody Toxin Conjugates Antibody Toxin Hybrid Antibody Toxin Hybrids Antibody-Toxin Conjugate Antibody-Toxin Conjugate, Monoclonal Antibody-Toxin Conjugates Antibody-Toxin Conjugates, Monoclonal Antibody-Toxin Hybrid Antibody-Toxin Hybrids Conjugate, Antibody-Toxin Conjugate, Cytotoxin-Antibody Conjugate, Monoclonal Antibody-Toxin Conjugate, Toxin-Antibody Conjugates, Antibody-Toxin Conjugates, Cytotoxin-Antibody Conjugates, Monoclonal Antibody-Toxin Conjugates, Toxin-Antibody Cytotoxin Antibody Conjugate Cytotoxin Antibody Conjugates Cytotoxin-Antibody Conjugate Cytotoxin-Antibody Conjugates Hybrid, Antibody-Toxin Hybrid, Toxin-Antibody Hybrids, Antibody-Toxin Hybrids, Toxin-Antibody Immunotoxin Monoclonal Antibody Toxin Conjugate Monoclonal Antibody Toxin Conjugates Monoclonal Antibody-Toxin Conjugate Monoclonal Antibody-Toxin Conjugates Toxin Antibody Conjugate Toxin Antibody Conjugates Toxin Antibody Hybrid Toxin Antibody Hybrids Toxin-Antibody Conjugate Toxin-Antibody Conjugates Toxin-Antibody Hybrid Toxin-Antibody Hybrids

UI del concepto	M0001375
Término preferido	Targeted Toxins
Término(s) alternativo(s)	Targeted Toxin Toxin, Targeted Toxins, Targeted

UI del concepto	M0001374
Término preferido	Toxins, Chimeric
Término(s) alternativo(s)	Carrier, Toxin Carriers, Toxin Chimeric Toxin Chimeric Toxins Conjugate, Toxin Conjugates, Toxin Toxin Carrier Toxin Carriers Toxin Conjugate Toxin Conjugates Toxin, Chimeric

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