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Descriptor en español: |
Factor de Necrosis Tumoral alfa
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Descriptor en inglés: | Tumor Necrosis Factor-alpha | ||||||
Descriptor en portugués: | Fator de Necrose Tumoral alfa | ||||||
Descriptor en francés: | Facteur de nécrose tumorale alpha | ||||||
Término(s) alternativo(s): |
Cachectin Cachectin Tumor Necrosis Factor Cachectin-Tumor Necrosis Factor TNF Superfamily, Member 2 TNF-alpha TNFalpha Tumor Necrosis Factor Tumor Necrosis Factor Ligand Superfamily Member 2 Tumor Necrosis Factor alpha |
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Código(s) jeráquico(s): |
D09.400.430.965 D12.644.276.374.500.800 D12.644.276.374.750.626 D12.776.124.900 D12.776.395.930 D12.776.467.374.500.800 D12.776.467.374.750.626 D23.529.374.500.800 D23.529.374.750.626 |
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Identificador Único RDF: | https://id.nlm.nih.gov/mesh/D014409 | ||||||
Nota de alcance: | Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS. |
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Calificadores permitidos: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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Indexación anterior: |
Endotoxins (1975-1987) Glycoproteins (1975-1987) Necrosis (1975-1987) |
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Nota Pública de MeSH: | 2005; see TUMOR NECROSIS FACTOR 1988-2005 |
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Nota de historia: | 2005(1988) |
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Vea también los descriptores: |
Adalimumab
MeSH Certolizumab Pegol MeSH Infliximab MeSH | ||||||
Identificador de DeCS: | 29591 | ||||||
ID del Descriptor: | D014409 | ||||||
Documentos indizados en la Biblioteca Virtual de Salud (BVS): | Haga clic aquí para acceder a los documentos de la BVS | ||||||
Fecha de establecimiento: | 01/01/1988 | ||||||
Fecha de entrada: | 08/05/1987 | ||||||
Fecha de revisión: | 20/06/2017 |
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CHEMICALS AND DRUGS
Carbohydrates [D09]Carbohydrates -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Biological Factors [D23]Biological Factors -
CHEMICALS AND DRUGS
Biological Factors [D23]Biological Factors
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Tumor Necrosis Factor-alpha
- Concepto preferido
UI del concepto |
M0022150 |
Nota de alcance | Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS. |
Término preferido | Tumor Necrosis Factor-alpha |
Término(s) alternativo(s) |
Cachectin Cachectin Tumor Necrosis Factor Cachectin-Tumor Necrosis Factor TNF Superfamily, Member 2 TNF-alpha TNFalpha Tumor Necrosis Factor Tumor Necrosis Factor Ligand Superfamily Member 2 Tumor Necrosis Factor alpha |
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