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Descriptor en español: |
ARN Interferente Pequeño
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Descriptor en inglés: | RNA, Small Interfering | ||||||
Descriptor en portugués: | RNA Interferente Pequeno | ||||||
Descriptor en francés: | Petit ARN interférent | ||||||
Término(s) alternativo(s): |
Hairpin RNA, Short Hairpin RNA, Small Interfering RNA, Short Interfering RNA, Small RNA, Scan RNA, Short Hairpin RNA, Short Interfering RNA, Small Hairpin RNA, Small Scan Repeat Associated siRNA Repeat-Associated siRNA Scan RNA Scan RNA, Small Short Hairpin RNA Short Interfering RNA Small Hairpin RNA Small Interfering RNA Small Scan RNA Trans Acting siRNA Trans-Acting siRNA scnRNA shRNA siRNA siRNA, Repeat Associated siRNA, Repeat-Associated siRNA, Trans Acting siRNA, Trans-Acting tasiRNA |
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Código(s) jeráquico(s): |
D13.150.650.700 D13.444.735.150.700 D13.444.735.790.552.875 |
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Identificador Único RDF: | https://id.nlm.nih.gov/mesh/D034741 | ||||||
Nota de alcance: | Small double-stranded, non-protein coding RNAs (21-31 nucleotides) involved in GENE SILENCING functions, especially RNA INTERFERENCE (RNAi). Endogenously, siRNAs are generated from dsRNAs (RNA, DOUBLE-STRANDED) by the same ribonuclease, Dicer, that generates miRNAs (MICRORNAS). The perfect match of the siRNAs' antisense strand to their target RNAs mediates RNAi by siRNA-guided RNA cleavage. siRNAs fall into different classes including trans-acting siRNA (tasiRNA), repeat-associated RNA (rasiRNA), small-scan RNA (scnRNA), and Piwi protein-interacting RNA (piRNA) and have different specific gene silencing functions. |
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Nota de indización: | Do not confuse with defective interfering RNA (diRNA), a viral RNA of DEFECTIVE VIRUSES. |
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Calificadores permitidos: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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Nota Pública de MeSH: | 2003; RNA, SMALL INTERFERING was indexed under RNA, UNTRANSLATED 2001-2002 |
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Nota de historia: | 2003; use RNA, SMALL INTERFERING (NM) 2001-2002 |
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Vea también los descriptores: |
MicroRNAs
MeSH RNA Interference MeSH RNA-Induced Silencing Complex MeSH | ||||||
Identificador de DeCS: | 37536 | ||||||
ID del Descriptor: | D034741 | ||||||
Documentos indizados en la Biblioteca Virtual de Salud (BVS): | Haga clic aquí para acceder a los documentos de la BVS | ||||||
Fecha de establecimiento: | 01/01/2003 | ||||||
Fecha de entrada: | 03/07/2002 | ||||||
Fecha de revisión: | 25/06/2010 |
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RNA, Small Interfering
- Concepto preferido
Short Hairpin RNA
- Más estrecho
Repeat-Associated siRNA
- Relacionado pero no más amplio ni más estrecho
Scan RNA
- Más estrecho
Trans-Acting siRNA
- Más estrecho
UI del concepto |
M0406100 |
Nota de alcance | Small double-stranded, non-protein coding RNAs (21-31 nucleotides) involved in GENE SILENCING functions, especially RNA INTERFERENCE (RNAi). Endogenously, siRNAs are generated from dsRNAs (RNA, DOUBLE-STRANDED) by the same ribonuclease, Dicer, that generates miRNAs (MICRORNAS). The perfect match of the siRNAs' antisense strand to their target RNAs mediates RNAi by siRNA-guided RNA cleavage. siRNAs fall into different classes including trans-acting siRNA (tasiRNA), repeat-associated RNA (rasiRNA), small-scan RNA (scnRNA), and Piwi protein-interacting RNA (piRNA) and have different specific gene silencing functions. |
Término preferido | RNA, Small Interfering |
Término(s) alternativo(s) |
Interfering RNA, Short Interfering RNA, Small RNA, Short Interfering Short Interfering RNA Small Interfering RNA siRNA |
UI del concepto |
M0543638 |
Término preferido | Short Hairpin RNA |
Término(s) alternativo(s) |
Hairpin RNA, Short Hairpin RNA, Small RNA, Short Hairpin RNA, Small Hairpin Small Hairpin RNA shRNA |
UI del concepto |
M0507096 |
Nota de alcance | siRNAs involved with GENE SILENCING of MOBILE GENETIC ELEMENTS in DROSOPHILA. |
Término preferido | Repeat-Associated siRNA |
Término(s) alternativo(s) |
Repeat Associated siRNA siRNA, Repeat Associated siRNA, Repeat-Associated |
UI del concepto |
M0507095 |
Nota de alcance | siRNAs, found in TETRAHYMENA, that are homologous to internal eliminated sequences (IESs) deleted during programmed genome rearrangement. |
Término preferido | Scan RNA |
Término(s) alternativo(s) |
RNA, Scan RNA, Small Scan Scan RNA, Small Small Scan RNA scnRNA |
UI del concepto |
M0507097 |
Nota de alcance | siRNA, found in plants, that are involved in silencing different gene loci than those from which they were derived. |
Término preferido | Trans-Acting siRNA |
Término(s) alternativo(s) |
Trans Acting siRNA siRNA, Trans Acting siRNA, Trans-Acting tasiRNA |
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