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| Descriptor en español: |
Factor de Crecimiento Epidérmico
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| Descriptor en inglés: | Epidermal Growth Factor | ||||||
| Descriptor en portugués: | Fator de Crescimento Epidérmico | ||||||
| Descriptor en francés: | Facteur de croissance épidermique | ||||||
| Término(s) alternativo(s): |
EGF Epidermal Growth Factor-Urogastrone Growth Factor, Epidermal Growth Factor-Urogastrone, Epidermal Human Urinary Gastric Inhibitor Urogastrone beta Urogastrone beta-Urogastrone |
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| Código(s) jeráquico(s): |
D06.472.317.350 D12.644.276.382.500 D12.776.467.382.500 D23.529.382.500 |
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| Identificador Único RDF: | https://id.nlm.nih.gov/mesh/D004815 | ||||||
| Nota de alcance: | A 6-kDa polypeptide growth factor initially discovered in mouse submaxillary glands. Human epidermal growth factor was originally isolated from urine based on its ability to inhibit gastric secretion and called urogastrone. Epidermal growth factor exerts a wide variety of biological effects including the promotion of proliferation and differentiation of mesenchymal and EPITHELIAL CELLS. It is synthesized as a transmembrane protein which can be cleaved to release a soluble active form. |
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| Calificadores permitidos: |
AA analogs & derivatives AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine |
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| Número de registro: | 62229-50-9 | ||||||
| Nombre CAS Tipo 1: | Epidermal growth factor | ||||||
| Indexación anterior: |
Gastrointestinal Hormones (1966-1974) Growth Substances (1966-1976) Peptides (1966-1976) |
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| Nota Pública de MeSH: | 2000; see EPIDERMAL GROWTH FACTOR-UROGASTRONE 1982-1999, see PEPTIDES 1977-1981; for UROGASTRONE see GASTROINTESTINAL HORMONES 1963-1981 |
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| Nota de historia: | 2000(1982); use PEPTIDES 1977-1981; for UROGASTRONE use GASTROINTESTINAL HORMONES 1963-1981 |
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| Vea también los descriptores: |
Anti-Ulcer Agents
MeSH ErbB Receptors MeSH Gastrointestinal Agents MeSH | ||||||
| Identificador de DeCS: | 4896 | ||||||
| ID del Descriptor: | D004815 | ||||||
| Clasificación de la NLM: | WK 170 | ||||||
| Documentos indizados en la Biblioteca Virtual de Salud (BVS): | Haga clic aquí para acceder a los documentos de la BVS | ||||||
| Fecha de establecimiento: | 01/01/1982 | ||||||
| Fecha de entrada: | 16/04/1976 | ||||||
| Fecha de revisión: | 02/07/2018 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Biological Factors [D23]Biological Factors
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Epidermal Growth Factor
- Concepto preferido
| UI del concepto |
M0007549 |
| Nota de alcance | A 6-kDa polypeptide growth factor initially discovered in mouse submaxillary glands. Human epidermal growth factor was originally isolated from urine based on its ability to inhibit gastric secretion and called urogastrone. Epidermal growth factor exerts a wide variety of biological effects including the promotion of proliferation and differentiation of mesenchymal and EPITHELIAL CELLS. It is synthesized as a transmembrane protein which can be cleaved to release a soluble active form. |
| Término preferido | Epidermal Growth Factor |
| Término(s) alternativo(s) |
EGF Epidermal Growth Factor-Urogastrone Growth Factor, Epidermal Growth Factor-Urogastrone, Epidermal Human Urinary Gastric Inhibitor Urogastrone beta Urogastrone beta-Urogastrone |
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