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Descriptor en español: |
Proteínas Mad2
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Descriptor en inglés: | Mad2 Proteins | ||||
Descriptor en portugués: | Proteínas Mad2 | ||||
Descriptor en francés: | Protéines Mad2 | ||||
Término(s) alternativo(s): |
Mad2 Mitotic Arrest Deficient-like 1 Proteins |
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Código(s) jeráquico(s): |
D12.776.167.313 D12.776.660.526 |
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Identificador Único RDF: | https://id.nlm.nih.gov/mesh/D064246 | ||||
Nota de alcance: | Mad2 is a component of the spindle-assembly checkpoint apparatus. It binds to and inhibits the Cdc20 activator subunit of the anaphase-promoting complex, preventing the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Mad2 is required for proper microtubule capture at KINETOCHORES. |
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Calificadores permitidos: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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Nota Pública de MeSH: | 2014; was indexed under CELL CYCLE PROTEINS 2000-2013 and NUCLEAR PROTEINS 2005-2013 |
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Nota de historia: | 2014 |
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Identificador de DeCS: | 55327 | ||||
ID del Descriptor: | D064246 | ||||
Documentos indizados en la Biblioteca Virtual de Salud (BVS): | Haga clic aquí para acceder a los documentos de la BVS | ||||
Fecha de establecimiento: | 01/01/2014 | ||||
Fecha de entrada: | 08/07/2013 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Mad2 Proteins
- Concepto preferido
UI del concepto |
M0580530 |
Nota de alcance | Mad2 is a component of the spindle-assembly checkpoint apparatus. It binds to and inhibits the Cdc20 activator subunit of the anaphase-promoting complex, preventing the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Mad2 is required for proper microtubule capture at KINETOCHORES. |
Término preferido | Mad2 Proteins |
Término(s) alternativo(s) |
Mad2 Mitotic Arrest Deficient-like 1 Proteins |
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