DeCS

Descriptor en español:

Proteínas ADAMTS

Español de España

Descriptor	proteínas ADAMTS
Término(s) alternativo(s)	proteasa ADAMTS proteasas ADAMTS proteína ADAMTS proteína ADAMTSL proteína desintegrina y metaloproteinasa con motivos de trombospondina proteína metalopeptidasa ADAM con motivo de trombospondina de tipo 1 proteína similar a ADAMTS proteínas ADAM con motivos de trombospondina proteínas ADAM metalopeptidasas con motivos trombospondina tipo 1 proteínas ADAMTSL proteínas tipo ADAMTS
Nota de alcance:	Subfamilia de proteasas ADAM que se distinguen por la presencia de una o más repeticiones de TROMBOSPONDINA tipo 1 (TSR). Se trata de motivos de tres cadenas que contienen residuos TRIPTÓFANO, ARGININA y CISTEÍNA, respectivamente. En contraste con las proteínas ADAM, que residen en las MEMBRANAS CELULARES, las proteasas ADAMTS se segregan y actúan en la MATRIZ EXTRACELULAR.

Descriptor en inglés:

ADAMTS Proteins

Descriptor en portugués:

Proteínas ADAMTS

Descriptor en francés:

Protéines ADAMTS

Término(s) alternativo(s):

A Disintegrin And Metalloproteinase With Thrombospondin Motifs Protein
A Disintegrin And Metalloproteinase With Thrombospondin Motifs Proteins
ADAMTS Like Protein
ADAMTS Like Proteins
ADAMTS Protease
ADAMTS Proteases
ADAMTS Protein
ADAMTS-Like Protein
ADAMTS-Like Proteins
ADAMTSL Protein
ADAMTSL Proteins
Adam Metallopeptidases With Thrombospondin Type 1 Motif Protein
Adam Metallopeptidases With Thrombospondin Type 1 Motif Proteins
Protease, ADAMTS
Protein, ADAMTS
Protein, ADAMTS-Like
Protein, ADAMTSL

Código(s) jeráquico(s):

D08.811.277.656.675.374.102.500
D09.400.430.500.500
D12.776.395.033.500
D12.776.860.300.085

Identificador Único RDF:

https://id.nlm.nih.gov/mesh/D000071096

Nota de alcance:

A subfamily of ADAM proteases that are distinguished by the presence of one or more THROMBOSPONDIN type-1 repeats (TSRs). These are three-strand motifs that contain characteristic TRYPTOPHAN, ARGININE, and CYSTEINE residues respectively. In contrast to ADAM proteins, which reside on CELL MEMBRANES, ADAMTS proteases are secreted and function in the EXTRACELLULAR MATRIX.

Calificadores permitidos:

AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine

UI del concepto	M000613119
Nota de alcance	A subfamily of ADAM proteases that are distinguished by the presence of one or more THROMBOSPONDIN type-1 repeats (TSRs). These are three-strand motifs that contain characteristic TRYPTOPHAN, ARGININE, and CYSTEINE residues respectively. In contrast to ADAM proteins, which reside on CELL MEMBRANES, ADAMTS proteases are secreted and function in the EXTRACELLULAR MATRIX.
Término preferido	ADAMTS Proteins
Término(s) alternativo(s)	A Disintegrin And Metalloproteinase With Thrombospondin Motifs Protein A Disintegrin And Metalloproteinase With Thrombospondin Motifs Proteins ADAMTS Protease ADAMTS Proteases ADAMTS Protein Adam Metallopeptidases With Thrombospondin Type 1 Motif Protein Adam Metallopeptidases With Thrombospondin Type 1 Motif Proteins Protease, ADAMTS Protein, ADAMTS

UI del concepto	M000613122
Nota de alcance	A subfamily of ADAMTS proteins that lack a protease domain.
Término preferido	ADAMTS-Like Proteins
Término(s) alternativo(s)	ADAMTS Like Protein ADAMTS Like Proteins ADAMTS-Like Protein ADAMTSL Protein ADAMTSL Proteins Protein, ADAMTS-Like Protein, ADAMTSL

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