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Descriptor en español: |
Proteína 12 Relacionada con la Autofagia
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Descriptor en inglés: | Autophagy-Related Protein 12 | ||||||
Descriptor en portugués: | Proteína 12 Relacionada à Autofagia | ||||||
Descriptor en francés: | Protéine-12 associée à l'autophagie | ||||||
Término(s) alternativo(s): |
ATG12 Protein ATG12, Ubiquitin-Like Protein Autophagy Related Protein 12 Ubiquitin Like Protein ATG12 Ubiquitin-Like Protein ATG12 |
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Código(s) jeráquico(s): |
D12.776.094.391 D12.776.947.125 |
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Identificador Único RDF: | https://id.nlm.nih.gov/mesh/D000071192 | ||||||
Nota de alcance: | A UBIQUITIN-like modifier protein that functions in AUTOPHAGOSOME formation, CYTOPLASM to VACUOLE transport, MITOPHAGY, and nucleophagy. Conjugation with ATG5 PROTEIN or ATG10 is essential for its function. The ATG12-ATG5 conjugate acts as an E3 UBIQUITIN LIGASE-like enzyme for lipid modification of ATG8 FAMILY PROTEINS and their localization to vesicle membranes. |
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Calificadores permitidos: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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Indexación anterior: |
Small Ubiquitin-Related Modifier Proteins (2008-2016) |
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Nota Pública de MeSH: | 2017 |
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Nota de historia: | 2017 |
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Identificador de DeCS: | 56558 | ||||||
ID del Descriptor: | D000071192 | ||||||
Documentos indizados en la Biblioteca Virtual de Salud (BVS): | Haga clic aquí para acceder a los documentos de la BVS | ||||||
Fecha de establecimiento: | 01/01/2017 | ||||||
Fecha de entrada: | 08/07/2016 | ||||||
Fecha de revisión: | 25/02/2016 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Autophagy-Related Protein 12
- Concepto preferido
UI del concepto |
M000613485 |
Nota de alcance | A UBIQUITIN-like modifier protein that functions in AUTOPHAGOSOME formation, CYTOPLASM to VACUOLE transport, MITOPHAGY, and nucleophagy. Conjugation with ATG5 PROTEIN or ATG10 is essential for its function. The ATG12-ATG5 conjugate acts as an E3 UBIQUITIN LIGASE-like enzyme for lipid modification of ATG8 FAMILY PROTEINS and their localization to vesicle membranes. |
Término preferido | Autophagy-Related Protein 12 |
Término(s) alternativo(s) |
ATG12 Protein ATG12, Ubiquitin-Like Protein Autophagy Related Protein 12 Ubiquitin Like Protein ATG12 Ubiquitin-Like Protein ATG12 |
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