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| Descriptor en español: |
Proteína de la Leucemia Promielocítica
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| Descriptor en inglés: | Promyelocytic Leukemia Protein | ||||||
| Descriptor en portugués: | Proteína da Leucemia Promielocítica | ||||||
| Descriptor en francés: | Protéine de la leucémie promyélocytaire | ||||||
| Término(s) alternativo(s): |
RNF71 Protein TRIM19 Protein |
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| Código(s) jeráquico(s): |
D12.776.624.776.654 D12.776.660.745 D12.776.930.713 D12.776.934.500 |
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| Identificador Único RDF: | https://id.nlm.nih.gov/mesh/D000071156 | ||||||
| Nota de alcance: | A tripartite motif protein that contains three ZINC FINGERS, including a RING FINGER DOMAIN, at its N-terminal. Several nuclear and one cytoplasmic isoforms result from alternative splicing of the PML gene; most nuclear isoforms localize to subnuclear structures (PML nuclear bodies) that are disrupted in ACUTE PROMYELOCYTIC LEUKEMIA cells. |
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| Calificadores permitidos: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Indexación anterior: |
Nuclear Proteins (2008-2016) Transcription Factors (2008-2016) Tumor Suppressor Proteins (2008-2016) |
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| Nota Pública de MeSH: | 2017 |
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| Nota de historia: | 2017 |
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| Identificador de DeCS: | 56647 | ||||||
| ID del Descriptor: | D000071156 | ||||||
| Documentos indizados en la Biblioteca Virtual de Salud (BVS): | Haga clic aquí para acceder a los documentos de la BVS | ||||||
| Fecha de establecimiento: | 01/01/2017 | ||||||
| Fecha de entrada: | 08/07/2016 | ||||||
| Fecha de revisión: | 26/02/2016 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Promyelocytic Leukemia Protein
- Concepto preferido
| UI del concepto |
M000613226 |
| Nota de alcance | A tripartite motif protein that contains three ZINC FINGERS, including a RING FINGER DOMAIN, at its N-terminal. Several nuclear and one cytoplasmic isoforms result from alternative splicing of the PML gene; most nuclear isoforms localize to subnuclear structures (PML nuclear bodies) that are disrupted in ACUTE PROMYELOCYTIC LEUKEMIA cells. |
| Término preferido | Promyelocytic Leukemia Protein |
| Término(s) alternativo(s) |
RNF71 Protein TRIM19 Protein |
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