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Descriptor en español: |
Katanina
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Descriptor en inglés: | Katanin | ||||
Descriptor en portugués: | Katanina | ||||
Descriptor en francés: | Katanine | ||||
Código(s) jeráquico(s): |
D08.811.277.040.013.500.250 D08.811.277.040.025.024.250 D12.776.157.025.750.250 D12.776.220.600.450.325 D12.776.631.560.338 |
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Identificador Único RDF: | https://id.nlm.nih.gov/mesh/D000074201 | ||||
Nota de alcance: | An enzyme (AAA ATPase) consisting of the 60 kDa ATPase subunit (p60 subunit A1) which severs MICROTUBULES, and an 80 kDa accessory protein (p80 subunit B1), which targets the enzyme to the CENTROSOME. It releases microtubules from the mitotic SPINDLE POLES to allow depolymerization and poleward motion of chromosomes. It is also a regulator of microtubule dynamics in NEURONAL OUTGROWTH. |
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Calificadores permitidos: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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Número de registro: | EC 5.6.1.1 | ||||
Nota Pública de MeSH: | 2018; KATANIN was indexed under ADENOSINE TRIPHOSPHATASES 1993-2017 |
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Nota de historia: | 2018 (1993) |
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Vea también los descriptores: |
AAA Domain
MeSH | ||||
Identificador de DeCS: | 56994 | ||||
ID del Descriptor: | D000074201 | ||||
Documentos indizados en la Biblioteca Virtual de Salud (BVS): | Haga clic aquí para acceder a los documentos de la BVS | ||||
Fecha de establecimiento: | 01/01/2018 | ||||
Fecha de entrada: | 11/07/2017 | ||||
Fecha de revisión: | 08/07/2019 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Katanin
- Concepto preferido
UI del concepto |
M000625785 |
Nota de alcance | An enzyme (AAA ATPase) consisting of the 60 kDa ATPase subunit (p60 subunit A1) which severs MICROTUBULES, and an 80 kDa accessory protein (p80 subunit B1), which targets the enzyme to the CENTROSOME. It releases microtubules from the mitotic SPINDLE POLES to allow depolymerization and poleward motion of chromosomes. It is also a regulator of microtubule dynamics in NEURONAL OUTGROWTH. |
Término preferido | Katanin |
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