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| Descriptor en español: |
Homólogo 4 de la Proteína Discs Large
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| Descriptor en inglés: | Disks Large Homolog 4 Protein | ||||||
| Descriptor en portugués: | Proteína 4 Homóloga a Disks-Large | ||||||
| Descriptor en francés: | Homologue-4 de la protéine Disks Large | ||||||
| Término(s) alternativo(s): |
Discs Large Homolog 4 Protein PSD 95 Protein PSD-95 Protein PSD95 Protein Postsynaptic Density Protein 95 SAP 90 Protein SAP-90 Protein SAP90 Protein Synapse Associated Protein 90 Synapse-Associated Protein 90 |
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| Código(s) jeráquico(s): |
D08.811.913.696.650.450.750 D12.644.360.265 D12.776.476.265 D12.776.543.219 D12.776.631.224 |
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| Identificador Único RDF: | https://id.nlm.nih.gov/mesh/D000076122 | ||||||
| Nota de alcance: | A neuronal protein consisting of three PDZ DOMAINS, an SH3 DOMAIN, and a C-terminal guanylate kinase-like region (see MAGUK PROTEINS). It localizes to the POST-SYNAPTIC DENSITY and associates with the cytoplasmic tail of NMDA RECEPTORS and SHAKER POTASSIUM CHANNELS, playing a critical role in NMDA receptor-mediated SYNAPTIC PLASTICITY. |
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| Calificadores permitidos: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Indexación anterior: |
Intracellular Signaling Peptides and Proteins (2005-2017) Membrane Proteins (2005-2017) |
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| Nota Pública de MeSH: | 2018 |
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| Nota de historia: | 2018 |
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| Vea también los descriptores: |
SAP90-PSD95 Associated Proteins
MeSH | ||||||
| Identificador de DeCS: | 57036 | ||||||
| ID del Descriptor: | D000076122 | ||||||
| Documentos indizados en la Biblioteca Virtual de Salud (BVS): | Haga clic aquí para acceder a los documentos de la BVS | ||||||
| Fecha de establecimiento: | 01/01/2018 | ||||||
| Fecha de entrada: | 11/07/2017 | ||||||
| Fecha de revisión: | 29/06/2017 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Disks Large Homolog 4 Protein
- Concepto preferido
| UI del concepto |
M000632224 |
| Nota de alcance | A neuronal protein consisting of three PDZ DOMAINS, an SH3 DOMAIN, and a C-terminal guanylate kinase-like region (see MAGUK PROTEINS). It localizes to the POST-SYNAPTIC DENSITY and associates with the cytoplasmic tail of NMDA RECEPTORS and SHAKER POTASSIUM CHANNELS, playing a critical role in NMDA receptor-mediated SYNAPTIC PLASTICITY. |
| Término preferido | Disks Large Homolog 4 Protein |
| Término(s) alternativo(s) |
Discs Large Homolog 4 Protein PSD 95 Protein PSD-95 Protein PSD95 Protein Postsynaptic Density Protein 95 SAP 90 Protein SAP-90 Protein SAP90 Protein Synapse Associated Protein 90 Synapse-Associated Protein 90 |
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