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Descriptor en español: |
Apelina
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Descriptor en inglés: | Apelin | ||||
Descriptor en portugués: | Apelina | ||||
Descriptor en francés: | Apeline | ||||
Código(s) jeráquico(s): |
D12.644.276.150 D23.529.134 |
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Identificador Único RDF: | https://id.nlm.nih.gov/mesh/D000073861 | ||||
Nota de alcance: | A 77 amino acid secreted endogenous ligand for the angiotensin II receptor-like 1 protein (APELIN RECEPTOR) that is proteolytically cleaved into four smaller peptides: Apelin-36, Apelin-31, Apelin-28, and Apelin-13. It inhibits entry of HIV into cells that express both APJ and CD4 ANTIGEN and is highly expressed in breast milk, where it may modulate the neonatal immune response. |
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Calificadores permitidos: |
AA analogs & derivatives AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine |
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Indexación anterior: |
Carrier Proteins (1998-2017) Intercellular Signaling Peptides and Proteins (2006-2017) |
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Nota Pública de MeSH: | 2018 |
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Nota de historia: | 2018 |
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Identificador de DeCS: | 57049 | ||||
ID del Descriptor: | D000073861 | ||||
Documentos indizados en la Biblioteca Virtual de Salud (BVS): | Haga clic aquí para acceder a los documentos de la BVS | ||||
Fecha de establecimiento: | 01/01/2018 | ||||
Fecha de entrada: | 11/07/2017 | ||||
Fecha de revisión: | 01/06/2017 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Biological Factors [D23]Biological Factors
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Apelin
- Concepto preferido
UI del concepto |
M000624130 |
Nota de alcance | A 77 amino acid secreted endogenous ligand for the angiotensin II receptor-like 1 protein (APELIN RECEPTOR) that is proteolytically cleaved into four smaller peptides: Apelin-36, Apelin-31, Apelin-28, and Apelin-13. It inhibits entry of HIV into cells that express both APJ and CD4 ANTIGEN and is highly expressed in breast milk, where it may modulate the neonatal immune response. |
Término preferido | Apelin |
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