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Descriptor en español: |
Factor Nuclear Tiroideo 1
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Descriptor en inglés: | Thyroid Nuclear Factor 1 | ||||||
Descriptor en portugués: | Fator Nuclear 1 de Tireoide | ||||||
Descriptor en francés: | Facteur-1 de transcription de la thyroïde | ||||||
Término(s) alternativo(s): |
Enhancer-Binding Protein, Thyroid-Specific Homeobox Protein Nkx 2.1 Homeobox Protein Nkx-2.1 NK2 Homeobox 1 Protein Nkx-2.1, Homeobox Protein TITF 1 Protein TITF-1 Protein TITF1 Protein TTF 1 Thyroid Nuclear Factor TTF-1 Thyroid Nuclear Factor Thyroid Specific Enhancer Binding Protein Thyroid Transcription Factor 1 Thyroid-Specific Enhancer-Binding Protein |
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Código(s) jeráquico(s): |
D12.776.260.400.871 D12.776.660.823 D12.776.930.888 |
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Identificador Único RDF: | https://id.nlm.nih.gov/mesh/D000074482 | ||||||
Nota de alcance: | A homeobox protein and transcription factor that localizes to the cell nucleus where it activates expression of thyroid specific genes such as THYROGLOBULIN and the THYROTROPIN RECEPTOR. It is critical for maintaining thyroid tissue in a differentiated state and also plays a role in lung development. Mutations in the NKX2-1 gene are associated with CHOREA, BENIGN HEREDITARY. |
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Calificadores permitidos: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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Nota Pública de MeSH: | 2018; THYROID NUCLEAR FACTOR 1 was indexed under NUCLEAR PROTEINS and TRANSCRIPTION FACTORS 1990-2017 |
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Nota de historia: | 2018 (1990) |
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Identificador de DeCS: | 57112 | ||||||
ID del Descriptor: | D000074482 | ||||||
Documentos indizados en la Biblioteca Virtual de Salud (BVS): | Haga clic aquí para acceder a los documentos de la BVS | ||||||
Fecha de establecimiento: | 01/01/2018 | ||||||
Fecha de entrada: | 11/07/2017 | ||||||
Fecha de revisión: | 06/04/2017 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Thyroid Nuclear Factor 1
- Concepto preferido
UI del concepto |
M0181663 |
Nota de alcance | A homeobox protein and transcription factor that localizes to the cell nucleus where it activates expression of thyroid specific genes such as THYROGLOBULIN and the THYROTROPIN RECEPTOR. It is critical for maintaining thyroid tissue in a differentiated state and also plays a role in lung development. Mutations in the NKX2-1 gene are associated with CHOREA, BENIGN HEREDITARY. |
Término preferido | Thyroid Nuclear Factor 1 |
Término(s) alternativo(s) |
Enhancer-Binding Protein, Thyroid-Specific Homeobox Protein Nkx 2.1 Homeobox Protein Nkx-2.1 NK2 Homeobox 1 Protein Nkx-2.1, Homeobox Protein TITF 1 Protein TITF-1 Protein TITF1 Protein TTF 1 Thyroid Nuclear Factor TTF-1 Thyroid Nuclear Factor Thyroid Specific Enhancer Binding Protein Thyroid Transcription Factor 1 Thyroid-Specific Enhancer-Binding Protein |
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