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Descriptor en español: |
Survivin
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Descriptor en inglés: | Survivin | ||||||
Descriptor en portugués: | Survivina | ||||||
Descriptor en francés: | Survivine | ||||||
Término(s) alternativo(s): |
BIRC5 Protein Baculoviral IAP Repeat containing Protein 5 Baculoviral IAP Repeat-containing Protein 5 |
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Código(s) jeráquico(s): |
D12.644.360.075.437.625 D12.776.167.576 D12.776.220.600.450.495 D12.776.476.075.437.625 |
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Identificador Único RDF: | https://id.nlm.nih.gov/mesh/D000077022 | ||||||
Nota de alcance: | An apoptosis inhibitory protein that contains a single baculoviral IAP repeat (BIR) domain. It associates with MICROTUBULES and functions to regulate cell proliferation as a component of the chromosome passage protein complex (CPC), performing essential roles for localization of the complex, chromosome alignment, segregation during MITOSIS and CYTOKINESIS, and assembly of the MITOTIC SPINDLE. It is expressed by fetal kidney and liver cells and highly expressed in ADENOCARCINOMA and high-grade LYMPHOMA. |
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Calificadores permitidos: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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Indexación anterior: |
Inhibitor of Apoptosis Proteins (2012-2018) Microtubule-Associated Proteins (1997-2018) Neoplasm Proteins (1997-2018) |
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Nota Pública de MeSH: | 2019 |
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Nota de historia: | 2019 |
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Identificador de DeCS: | 57504 | ||||||
ID del Descriptor: | D000077022 | ||||||
Documentos indizados en la Biblioteca Virtual de Salud (BVS): | Haga clic aquí para acceder a los documentos de la BVS | ||||||
Fecha de establecimiento: | 01/01/2019 | ||||||
Fecha de entrada: | 09/07/2018 | ||||||
Fecha de revisión: | 16/01/2018 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
|
Survivin
- Concepto preferido
UI del concepto |
M000639155 |
Nota de alcance | An apoptosis inhibitory protein that contains a single baculoviral IAP repeat (BIR) domain. It associates with MICROTUBULES and functions to regulate cell proliferation as a component of the chromosome passage protein complex (CPC), performing essential roles for localization of the complex, chromosome alignment, segregation during MITOSIS and CYTOKINESIS, and assembly of the MITOTIC SPINDLE. It is expressed by fetal kidney and liver cells and highly expressed in ADENOCARCINOMA and high-grade LYMPHOMA. |
Término preferido | Survivin |
Término(s) alternativo(s) |
BIRC5 Protein Baculoviral IAP Repeat containing Protein 5 Baculoviral IAP Repeat-containing Protein 5 |
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