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Descripteur en français: Oncogènes
Descripteur en anglais: Oncogenes
Descripteur en espagnol: Oncogenes
Descripteur oncogenes
Synonymes genes transformantes
Note d'application: Genes cuya ganancia de función da lugar a TRANSFORMACIÓN NEOPLÁSICA CELULAR. Comprenden, por ejemplo, los genes de activadores o estimuladores de la PROLIFERACIÓN CELULAR, como factores de crecimiento, receptores de factores de crecimiento, proteína cinasas, transductores de señales, fosfoproteínas nucleares y factores de transcripción. El prefijo "v-" antes del símbolo de un oncogén indica que se trata de oncogenes capturados y transmitidos por RETROVIRUS; el prefijo "c-" antes del símbolo de un oncogén indica que se trata del homólogo celular (PROTO-ONCOGENES) de un v-oncogén.
Descripteur en portugais: Oncogenes
Synonymes: Gene, Transforming
Genes, Transforming
Oncogene
Transforming Gene
Transforming Genes
Code(s) d'arborescence: G05.360.340.024.340.375.500
Identificateur unique RDF: https://id.nlm.nih.gov/mesh/D009857
Note d'application: Genes whose gain-of-function alterations lead to NEOPLASTIC CELL TRANSFORMATION. They include, for example, genes for activators or stimulators of CELL PROLIFERATION such as growth factors, growth factor receptors, protein kinases, signal transducers, nuclear phosphoproteins, and transcription factors. A prefix of "v-" before oncogene symbols indicates oncogenes captured and transmitted by RETROVIRUSES; the prefix "c-" before the gene symbol of an oncogene indicates it is the cellular homolog (PROTO-ONCOGENES) of a v-oncogene.
Note d'indexation: "oncogene" used by author may refer to ONCOGENES or PROTO-ONCOGENES; do not confuse with ONCOGENS see CARCINOGENS; Manual 24.4.4.3; do not confuse with GENES, NEOPLASM
Qualificatifs autorisés: DE drug effects
ES ethics
GE genetics
IM immunology
PH physiology
RE radiation effects
Indexation précédente: Genes (1966-1977)
Genes, Viral (1978-1982)
Note publique MeSH: 83
Note historique: 83
Identifiant DeCS: 10040
ID du Descripteur: D009857
Classification de la NLM: QZ 210
Documents indexés dans la Biblioteque Virtuelle de Santé (BVS): Cliquez ici pour accéder aux documents VHL
Date d'établissement: 01/01/1983
Date d'entrée: 22/04/1982
Date de révision: 08/07/2008
Oncogenes - Concept préféré
Concept UI M0015298
Note d'application Genes whose gain-of-function alterations lead to NEOPLASTIC CELL TRANSFORMATION. They include, for example, genes for activators or stimulators of CELL PROLIFERATION such as growth factors, growth factor receptors, protein kinases, signal transducers, nuclear phosphoproteins, and transcription factors. A prefix of "v-" before oncogene symbols indicates oncogenes captured and transmitted by RETROVIRUSES; the prefix "c-" before the gene symbol of an oncogene indicates it is the cellular homolog (PROTO-ONCOGENES) of a v-oncogene.
Terme préféré Oncogenes
Synonymes Gene, Transforming
Genes, Transforming
Oncogene
Transforming Gene
Transforming Genes



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