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Descripteur en français: | Région variable d'immunoglobuline | ||||||
Descripteur en anglais: | Immunoglobulin Variable Region | ||||||
Descripteur en espagnol: |
Región Variable de Inmunoglobulina
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Descripteur en portugais: | Região Variável de Imunoglobulina | ||||||
Synonymes: |
Antibody Fragment, Fv Antibody Fragments, Fv Fragment, Fv Fragment, Fv Antibody Fragment, Immunoglobulin Fv Fragments, Fv Fragments, Fv Antibody Fragments, Immunoglobulin Fv Framework Region, Ig Framework Region, Immunoglobulin Framework Regions, Ig Framework Regions, Immunoglobulin Fv Antibody Fragment Fv Antibody Fragments Fv Fragment Fv Fragment, Immunoglobulin Fv Fragments Fv Fragments, Immunoglobulin Ig Framework Region Ig Framework Regions Ig Variable Region Ig Variable Regions Immunoglobulin Framework Region Immunoglobulin Framework Regions Immunoglobulin Fv Fragment Immunoglobulin Fv Fragments Immunoglobulin V Immunoglobulin Variable Regions Regions, Immunoglobulin Variable Variable Region, Ig Variable Region, Immunoglobulin Variable Regions, Ig Variable Regions, Immunoglobulin |
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Code(s) d'arborescence: |
D12.644.541.500.650.500 D12.776.124.486.485.680.650.500 D12.776.124.486.485.797 D12.776.124.790.651.680.650.500 D12.776.124.790.651.797 D12.776.377.715.548.680.650.500 D12.776.377.715.548.797 G02.111.570.060.425 |
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Identificateur unique RDF: | https://id.nlm.nih.gov/mesh/D007135 | ||||||
Note d'application: | That region of the immunoglobulin molecule that varies in its amino acid sequence and composition, and comprises the binding site for a specific antigen. It is located at the N-terminus of the Fab fragment of the immunoglobulin. It includes hypervariable regions (COMPLEMENTARITY DETERMINING REGIONS) and framework regions. |
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Qualificatifs autorisés: |
AD administration & dosage AE adverse effects AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification DE drug effects EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PO poisoning RE radiation effects TO toxicity TU therapeutic use UL ultrastructure UR urine |
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Action Pharmacologique: |
Facteurs immunologiques |
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Indexation précédente: |
Antigenic Determinants (1972-1976) Binding Sites, Antibody (1973-1976) Immunoglobulin Fragments (1973-1976) Immunoglobulins, Fab (1973-1976) |
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Note publique MeSH: | 84; was see under BINDING SITES, ANTIBODY 1977-83 |
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Note historique: | 84(77); was see under BINDING SITES, ANTIBODY 1977-83 |
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Voir aussi le(s) descripteur(s): |
Binding Sites, Antibody
MeSH Immunoglobulin Domains MeSH | ||||||
Identifiant DeCS: | 22209 | ||||||
ID du Descripteur: | D007135 | ||||||
Documents indexés dans la Biblioteque Virtuelle de Santé (BVS): | Cliquez ici pour accéder aux documents VHL | ||||||
Date d'établissement: | 01/01/1984 | ||||||
Date d'entrée: | 16/04/1976 | ||||||
Date de révision: | 20/11/2015 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
PHENOMENA AND PROCESSES
Chemical Phenomena [G02]Chemical Phenomena
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Immunoglobulin Variable Region
- Concept préféré
Immunoglobulin Fv Fragments
- Connexes mais pas plus larges ou plus étroites
Framework Region, Immunoglobulin
- Plus spécifique
Concept UI |
M0011118 |
Note d'application | That region of the immunoglobulin molecule that varies in its amino acid sequence and composition, and comprises the binding site for a specific antigen. It is located at the N-terminus of the Fab fragment of the immunoglobulin. It includes hypervariable regions (COMPLEMENTARITY DETERMINING REGIONS) and framework regions. |
Terme préféré | Immunoglobulin Variable Region |
Synonymes |
Ig Variable Region Ig Variable Regions Immunoglobulin V Immunoglobulin Variable Regions Regions, Immunoglobulin Variable Variable Region, Ig Variable Region, Immunoglobulin Variable Regions, Ig Variable Regions, Immunoglobulin |
Concept UI |
M0560635 |
Note d'application | The paired immunoglobulin fragments composed of the variable domains of the heavy and light chains. |
Terme préféré | Immunoglobulin Fv Fragments |
Synonymes |
Antibody Fragment, Fv Antibody Fragments, Fv Fragment, Fv Fragment, Fv Antibody Fragment, Immunoglobulin Fv Fragments, Fv Fragments, Fv Antibody Fragments, Immunoglobulin Fv Fv Antibody Fragment Fv Antibody Fragments Fv Fragment Fv Fragment, Immunoglobulin Fv Fragments Fv Fragments, Immunoglobulin Immunoglobulin Fv Fragment |
Concept UI |
M0011116 |
Terme préféré | Framework Region, Immunoglobulin |
Synonymes |
Framework Region, Ig Framework Regions, Ig Framework Regions, Immunoglobulin Ig Framework Region Ig Framework Regions Immunoglobulin Framework Region Immunoglobulin Framework Regions |
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