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Descripteur en français: Polypeptide pancréatique
Descripteur en anglais: Pancreatic Polypeptide
Descripteur en espagnol: Polipéptido Pancreático
Descripteur polipéptido pancreático
Note d'application: Hormona pancreática de 36 aminoácidos que es segregada principalmente por células endocrinas que se encuentran en la periferia de los ISLOTES DE LANGERHANS y adyacentes a células que contienen SOMATOSTATINA y GLUCAGÓN. El polipéptido pancreático (PP), cuando se administra periféricamente, puede inhibir la secreción gástrica, el vaciamiento gástrico, la secreción de enzimas pancreáticas y el apetito. La ausencia de polipéptido pancreático se ha asociado a la OBESIDAD en ratas y ratones.
Descripteur en portugais: Polipeptídeo Pancreático
Synonymes: Pancreatic Polypeptide (PP)
Pancreatic Polypeptide Hormone
Pancreatic Prohormone
Code(s) d'arborescence: D06.472.699.587.700
D12.644.400.600
D12.644.548.586.700
D12.776.631.650.600
Identificateur unique RDF: https://id.nlm.nih.gov/mesh/D010191
Note d'application: A 36-amino acid pancreatic hormone that is secreted mainly by endocrine cells found at the periphery of the ISLETS OF LANGERHANS and adjacent to cells containing SOMATOSTATIN and GLUCAGON. Pancreatic polypeptide (PP), when administered peripherally, can suppress gastric secretion, gastric emptying, pancreatic enzyme secretion, and appetite. A lack of pancreatic polypeptide (PP) has been associated with OBESITY in rats and mice.
Qualificatifs autorisés: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Action Pharmacologique: Agents gastro-intestinaux
Hormones
Numéro de registre: 59763-91-6
Indexation précédente: Hormones (1966-1973)
Pancreatic Hormones (1974-1978)
Peptides (1966-1978)
Note publique MeSH: 79
Note historique: 79
Identifiant DeCS: 22598
ID du Descripteur: D010191
Documents indexés dans la Biblioteque Virtuelle de Santé (BVS): Cliquez ici pour accéder aux documents VHL
Date d'établissement: 01/01/1979
Date d'entrée: 18/05/1978
Date de révision: 24/11/2015
Pancreatic Polypeptide - Concept préféré
Concept UI M0015804
Note d'application A 36-amino acid pancreatic hormone that is secreted mainly by endocrine cells found at the periphery of the ISLETS OF LANGERHANS and adjacent to cells containing SOMATOSTATIN and GLUCAGON. Pancreatic polypeptide (PP), when administered peripherally, can suppress gastric secretion, gastric emptying, pancreatic enzyme secretion, and appetite. A lack of pancreatic polypeptide (PP) has been associated with OBESITY in rats and mice.
Terme préféré Pancreatic Polypeptide
Synonymes Pancreatic Polypeptide (PP)
Pancreatic Polypeptide Hormone
Pancreatic Prohormone - Plus large
Concept UI M0496467
Note d'application A secreted polypeptide of about 100 amino acids, depending on the species, from the PANCREASE. It is the precursor of pancreatic polypeptide (PP) and a pancreatic C-terminal peptide or pancreatic icosapeptide.
Terme préféré Pancreatic Prohormone



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