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Descripteur en français: | Somatostatine | ||||||
Descripteur en anglais: | Somatostatin | ||||||
Descripteur en espagnol: |
Somatostatina
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Descripteur en portugais: | Somatostatina | ||||||
Synonymes: |
Cyclic Somatostatin SRIH-14 Somatofalk Somatostatin 14 Somatostatin, Cyclic Somatostatin-14 Somatotropin Release Inhibiting Factor Somatotropin Release Inhibiting Hormone Somatotropin Release-Inhibiting Factor Somatotropin Release-Inhibiting Hormone Stilamin |
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Code(s) d'arborescence: |
D06.472.699.327.700.875 D06.472.699.587.780 D12.644.400.400.700.875 D12.644.548.365.700.875 D12.644.548.586.780 D12.776.631.650.405.700.875 |
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Identificateur unique RDF: | https://id.nlm.nih.gov/mesh/D013004 | ||||||
Note d'application: | A 14-amino acid peptide named for its ability to inhibit pituitary GROWTH HORMONE release, also called somatotropin release-inhibiting factor. It is expressed in the central and peripheral nervous systems, the gut, and other organs. SRIF can also inhibit the release of THYROID-STIMULATING HORMONE; PROLACTIN; INSULIN; and GLUCAGON besides acting as a neurotransmitter and neuromodulator. In a number of species including humans, there is an additional form of somatostatin, SRIF-28 with a 14-amino acid extension at the N-terminal. |
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Qualificatifs autorisés: |
AA analogs & derivatives AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine |
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Action Pharmacologique: |
Hormones |
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Numéro de registre: | 51110-01-1 | ||||||
Indexation précédente: |
Somatotropin Releasing Hormone/antagonists & inhibitors (1974) Somatotropin/antagonists & inhibitors (1973-1974) |
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Note publique MeSH: | 99 |
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Note Online: | use SOMATOSTATIN to search SOMATOTROPIN RELEASE INHIBITING HORMONE 1975-84 |
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Note historique: | 99 |
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Voir aussi le(s) descripteur(s): |
Receptors, Somatostatin
MeSH | ||||||
Identifiant DeCS: | 22676 | ||||||
ID du Descripteur: | D013004 | ||||||
Classification de la NLM: | WK 515 | ||||||
Documents indexés dans la Biblioteque Virtuelle de Santé (BVS): | Cliquez ici pour accéder aux documents VHL | ||||||
Date d'établissement: | 01/09/1975 | ||||||
Date d'entrée: | 11/11/1974 | ||||||
Date de révision: | 24/11/2015 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Somatostatin
- Concept préféré
Stilamin
- Plus spécifique
Somatofalk
- Plus spécifique
Concept UI |
M0020152 |
Note d'application | A 14-amino acid peptide named for its ability to inhibit pituitary GROWTH HORMONE release, also called somatotropin release-inhibiting factor. It is expressed in the central and peripheral nervous systems, the gut, and other organs. SRIF can also inhibit the release of THYROID-STIMULATING HORMONE; PROLACTIN; INSULIN; and GLUCAGON besides acting as a neurotransmitter and neuromodulator. In a number of species including humans, there is an additional form of somatostatin, SRIF-28 with a 14-amino acid extension at the N-terminal. |
Terme préféré | Somatostatin |
Synonymes |
Cyclic Somatostatin SRIH-14 Somatostatin 14 Somatostatin, Cyclic Somatostatin-14 Somatotropin Release Inhibiting Factor Somatotropin Release Inhibiting Hormone Somatotropin Release-Inhibiting Factor Somatotropin Release-Inhibiting Hormone |
Concept UI |
M0020154 |
Terme préféré | Stilamin |
Concept UI |
M0020153 |
Terme préféré | Somatofalk |
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