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Descripteur en français: Vieillissement de la cellule
Descripteur en anglais: Cellular Senescence
Descripteur en espagnol: Senescencia Celular
Descripteur senescencia celular
Synonymes envejecimiento celular
envejecimiento de la célula
senescencia de la célula
senescencia replicadora
Note d'application: Disminución, con el paso del tiempo, de la capacidad proliferativa de las células. Cada célula está programada para realizar determinado número de divisiones celulares y, al finalizar dicho tiempo, la proliferación se interrumpe y la célula entra en un estado de inactividad tras el cual se produce la MUERTE CELULAR a través del proceso de APOPTOSIS.
Descripteur en portugais: Senescência Celular
Synonymes: Ageing, Cell
Ageing, Cellular
Aging, Cell
Aging, Cellular
Cell Ageing
Cell Aging
Cell Senescence
Cellular Ageing
Cellular Aging
Replicative Senescence
Senescence, Cell
Senescence, Cellular
Senescence, Replicative
Code(s) d'arborescence: G04.043
G07.345.124.130
Identificateur unique RDF: https://id.nlm.nih.gov/mesh/D016922
Note d'application: Process by which cells irreversibly stop dividing and enter a state of permanent growth arrest without undergoing CELL DEATH. Senescence can be induced by DNA DAMAGE or other cellular stresses, such as OXIDATIVE STRESS.
Note d'indexation: not for micro-organisms
Qualificatifs autorisés: DE drug effects
GE genetics
IM immunology
PH physiology
RE radiation effects
Indexation précédente: Cell Survival (1977-1991)
Erythrocyte Aging (1967-1991)
Note publique MeSH: 2018; see CELL AGING 1992-2017; see CELL SURVIVAL 1977-1991; for CELL SENESCENCE and SENESCENCE, CELLULAR see CELL SURVIVAL 1991
Note historique: 2018 (1992); use CELL SURVIVAL 1977-1991
Voir aussi le(s) descripteur(s): Cell Death MeSH
Identifiant DeCS: 30205
ID du Descripteur: D016922
Documents indexés dans la Biblioteque Virtuelle de Santé (BVS): Cliquez ici pour accéder aux documents VHL
Date d'établissement: 01/01/1992
Date d'entrée: 30/05/1991
Date de révision: 22/06/2017
Cellular Senescence - Concept préféré
Concept UI M0025749
Note d'application Process by which cells irreversibly stop dividing and enter a state of permanent growth arrest without undergoing CELL DEATH. Senescence can be induced by DNA DAMAGE or other cellular stresses, such as OXIDATIVE STRESS.
Terme préféré Cellular Senescence
Synonymes Cell Senescence
Senescence, Cell
Senescence, Cellular
Cell Aging - Plus spécifique
Concept UI M000630817
Note d'application Cellular senescence during AGING or due to extended passages of normal cells in culture and that is triggered by the DNA damage-response to TELOMERE SHORTENING or by repeated exposure to stress signals.
Terme préféré Cell Aging
Synonymes Ageing, Cell
Ageing, Cellular
Aging, Cell
Aging, Cellular
Cell Ageing
Cellular Ageing
Cellular Aging
Replicative Senescence
Senescence, Replicative



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