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Descripteur en français: Ubiquitine
Descripteur en anglais: Ubiquitin
Descripteur en espagnol: Ubiquitina
Descripteur ubicuitina
Note d'application: Polipéptido de 76 aminoácidos muy conservado que se encuentra en células eucariotas y actúa como marcador en el TRANSPORTE y la degradación de proteínas intracelulares. La ubicuitina se activa a través de una serie de pasos complejos y forma un enlace isopeptídico con residuos de lisina de proteínas específicas en el interior de la célula. Estas proteíns "ubicuitinadas" pueden ser reconocidas y degradadas por proteosomas o pueden ser transportadas a compartimientos específicos dentro de la célula.
Descripteur en portugais: Ubiquitina
Synonymes: APF-1
ATP Dependent Proteolysis Factor 1
ATP-Dependent Proteolysis Factor 1
HMG-20
High Mobility Protein 20
Human Ubiquitin
Ubiquitin, Human
Code(s) d'arborescence: D12.776.947.500
Identificateur unique RDF: https://id.nlm.nih.gov/mesh/D025801
Note d'application: A highly conserved 76-amino acid peptide universally found in eukaryotic cells that functions as a marker for intracellular PROTEIN TRANSPORT and degradation. Ubiquitin becomes activated through a series of complicated steps and forms an isopeptide bond to lysine residues of specific proteins within the cell. These "ubiquitinated" proteins can be recognized and degraded by proteosomes or be transported to specific compartments within the cell.
Note d'indexation: UBIQUITINS is also available
Qualificatifs autorisés: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Indexation précédente: Chromosomal Proteins, Non-Histone (1977-1984)
Nucleoproteins (1966-1977)
Peptides (1975-1980)
Ubiquitins (1985-2001)
Note publique MeSH: 2002; see UBIQUITINS (1985-2001)
Note historique: 2002; use UBIQUITINS (1985-2001)
Identifiant DeCS: 36260
ID du Descripteur: D025801
Documents indexés dans la Biblioteque Virtuelle de Santé (BVS): Cliquez ici pour accéder aux documents VHL
Date d'établissement: 01/01/2002
Date d'entrée: 25/07/2001
Date de révision: 05/06/2015
Ubiquitin - Concept préféré
Concept UI M0369737
Note d'application A highly conserved 76-amino acid peptide universally found in eukaryotic cells that functions as a marker for intracellular PROTEIN TRANSPORT and degradation. Ubiquitin becomes activated through a series of complicated steps and forms an isopeptide bond to lysine residues of specific proteins within the cell. These "ubiquitinated" proteins can be recognized and degraded by proteosomes or be transported to specific compartments within the cell.
Terme préféré Ubiquitin
Synonymes APF-1
ATP Dependent Proteolysis Factor 1
ATP-Dependent Proteolysis Factor 1
HMG-20
High Mobility Protein 20
Ubiquitin, Human - Plus spécifique
Concept UI M0329583
Terme préféré Ubiquitin, Human
Synonymes Human Ubiquitin



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