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Descripteur en français: Idiotypes des immunoglobulines
Descripteur en anglais: Immunoglobulin Idiotypes
Descripteur en espagnol: Idiotipos de Inmunoglobulinas
Descripteur idiotipos de inmunoglobulinas
Synonymes idiotipos de Ig
Note d'application: Determinantes singulares controlados genéticamente presentes en los ANTICUERPOS cuya especificidad está limitada a un único grupo de proteínas (p. ej., otra molécula de anticuerpo o una proteína individual de mieloma). Parece que el idiotipo representa la antigenicidad del sitio de unión al antígeno del anticuerpo y que está codeterminado genéticamente con él. Se han localizado de modo preciso los determinantes idiotípicos en la REGIÓN VARIABLE DE LAS INMUNOGLOBULINAS de ambas cadenas polipeptídicas de las inmunoglobulinas.
Descripteur en portugais: Idiótipos de Imunoglobulinas
Synonymes: Idiotype, Ig
Idiotype, Immunoglobulin
Idiotypes, Ig
Idiotypes, Immunoglobulin
Ig Idiotype
Ig Idiotypes
Immunoglobulin Idiotype
Code(s) d'arborescence: D12.644.541.500.745
D12.776.124.486.485.680.745
D12.776.124.790.651.680.745
D12.776.377.715.548.680.745
D23.050.550.750
G02.111.570.060.425.580
G12.500.450
Identificateur unique RDF: https://id.nlm.nih.gov/mesh/D007130
Note d'application: Unique genetically-controlled determinants present on ANTIBODIES whose specificity is limited to a single group of proteins (e.g., another antibody molecule or an individual myeloma protein). The idiotype appears to represent the antigenicity of the antigen-binding site of the antibody and to be genetically codetermined with it. The idiotypic determinants have been precisely located to the IMMUNOGLOBULIN VARIABLE REGION of both immunoglobin polypeptide chains.
Qualificatifs autorisés: AD administration & dosage
AE adverse effects
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
DE drug effects
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PO poisoning
RE radiation effects
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Action Pharmacologique: Facteurs immunologiques
Indexation précédente: Anti-Antibodies (1966-1969)
Antibody Specificity (1970-1978)
Antigenic Determinants (1970-1978)
Binding Sites, Antibody (1973-1978)
Note publique MeSH: 79
Note historique: 79
Version alternative: IG IDIOTYPES
Identifiant DeCS: 7313
ID du Descripteur: D007130
Classification de la NLM: QW 601
Documents indexés dans la Biblioteque Virtuelle de Santé (BVS): Cliquez ici pour accéder aux documents VHL
Date d'établissement: 01/01/1979
Date d'entrée: 27/01/1978
Date de révision: 05/07/2019
Immunoglobulin Idiotypes - Concept préféré
Concept UI M0011109
Note d'application Unique genetically-controlled determinants present on ANTIBODIES whose specificity is limited to a single group of proteins (e.g., another antibody molecule or an individual myeloma protein). The idiotype appears to represent the antigenicity of the antigen-binding site of the antibody and to be genetically codetermined with it. The idiotypic determinants have been precisely located to the IMMUNOGLOBULIN VARIABLE REGION of both immunoglobin polypeptide chains.
Terme préféré Immunoglobulin Idiotypes
Synonymes Idiotype, Ig
Idiotype, Immunoglobulin
Idiotypes, Ig
Idiotypes, Immunoglobulin
Ig Idiotype
Ig Idiotypes
Immunoglobulin Idiotype



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