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| Descripteur en français: | Kératines | ||||||
| Descripteur en anglais: | Keratins | ||||||
| Descripteur en espagnol: |
Queratinas
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| Descripteur en portugais: | Queratinas | ||||||
| Synonymes: |
Associated Protein, Keratin Cytokeratin Keratin Keratin Associated Protein Keratin Associated Proteins Keratin-Associated Proteins Protein, Keratin Associated alpha Keratin alpha-Keratin |
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| Code(s) d'arborescence: |
D05.750.078.593.450 D12.776.220.475.450 D12.776.860.607 |
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| Identificateur unique RDF: | https://id.nlm.nih.gov/mesh/D007633 | ||||||
| Note d'application: | A class of fibrous proteins or scleroproteins that represents the principal constituent of EPIDERMIS; HAIR; NAILS; horny tissues, and the organic matrix of tooth ENAMEL. Two major conformational groups have been characterized, alpha-keratin, whose peptide backbone forms a coiled-coil alpha helical structure consisting of TYPE I KERATIN and a TYPE II KERATIN, and beta-keratin, whose backbone forms a zigzag or pleated sheet structure. alpha-Keratins have been classified into at least 20 subtypes. In addition multiple isoforms of subtypes have been found which may be due to GENE DUPLICATION. |
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| Qualificatifs autorisés: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Numéro de registre: | 68238-35-7 | ||||||
| Note publique MeSH: | 2007; see KERATIN 1966-2006; KERATIN-ASSOCIATED PROTEINS was indexed under KERATIN 2000-2006, & under PROTEINS 1993-1999 |
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| Note historique: | 2007(1966) |
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| Voir aussi le(s) descripteur(s): |
Intermediate Filaments
MeSH Keratinocytes MeSH | ||||||
| Identifiant DeCS: | 7802 | ||||||
| ID du Descripteur: | D007633 | ||||||
| Classification de la NLM: | QU 55.3 | ||||||
| Documents indexés dans la Biblioteque Virtuelle de Santé (BVS): | Cliquez ici pour accéder aux documents VHL | ||||||
| Date d'établissement: | 01/01/2007 | ||||||
| Date d'entrée: | 01/01/1999 | ||||||
| Date de révision: | 27/05/2020 |
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CHEMICALS AND DRUGS
Macromolecular Substances [D05]Macromolecular Substances -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Keratins
- Concept préféré
Keratin-Associated Proteins
- Plus spécifique
alpha-Keratin
- Plus spécifique
| Concept UI |
M0011957 |
| Note d'application | A class of fibrous proteins or scleroproteins that represents the principal constituent of EPIDERMIS; HAIR; NAILS; horny tissues, and the organic matrix of tooth ENAMEL. Two major conformational groups have been characterized, alpha-keratin, whose peptide backbone forms a coiled-coil alpha helical structure consisting of TYPE I KERATIN and a TYPE II KERATIN, and beta-keratin, whose backbone forms a zigzag or pleated sheet structure. alpha-Keratins have been classified into at least 20 subtypes. In addition multiple isoforms of subtypes have been found which may be due to GENE DUPLICATION. |
| Terme préféré | Keratins |
| Synonymes |
Cytokeratin Keratin |
| Concept UI |
M0213667 |
| Terme préféré | Keratin-Associated Proteins |
| Synonymes |
Associated Protein, Keratin Keratin Associated Protein Keratin Associated Proteins Protein, Keratin Associated |
| Concept UI |
M0494274 |
| Terme préféré | alpha-Keratin |
| Synonymes |
alpha Keratin |
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