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Descripteur en français: Muscimol
Descripteur en anglais: Muscimol
Descripteur en espagnol: Muscimol
Descripteur muscimol
Synonymes agarin
panterina
Note d'application: Isoxazol neurotóxico aislado de la Amanita muscaria y A. phalloides, que también se obtiene mediante descarboxilación del ÁCIDO IBOTÉNICO. Es un potente agonista de los receptores GABA-A y se utiliza principalmente como herramienta experimental en estudios sobre animales y tejidos.
Descripteur en portugais: Muscimol
Synonymes: Agarin
Pantherine
Code(s) d'arborescence: D03.383.129.462.470
D23.946.587.587
Identificateur unique RDF: https://id.nlm.nih.gov/mesh/D009118
Note d'application: A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
Qualificatifs autorisés: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Action Pharmacologique: Agonistes du récepteur GABA-A
Numéro de registre: 2763-96-4
Nom CAS Type 1: 3(2H)-Isoxazolone, 5-(aminomethyl)-
Indexation précédente: Mycotoxins (1967-1978)
Oxazoles (1966-1978)
Toxins (1966)
Note publique MeSH: 86; was see under OXAZOLES 1979-85
Note historique: 86(79); was see under OXAZOLES 1979-85
Voir aussi le(s) descripteur(s): Receptors, GABA-A MeSH
Identifiant DeCS: 9308
ID du Descripteur: D009118
Documents indexés dans la Biblioteque Virtuelle de Santé (BVS): Cliquez ici pour accéder aux documents VHL
Date d'établissement: 01/01/1986
Date d'entrée: 03/05/1978
Date de révision: 31/05/2016
Muscimol - Concept préféré
Concept UI M0014231
Note d'application A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
Terme préféré Muscimol
Synonymes Agarin
Pantherine



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