Pesquisa
Descritor em português: Imunoglobulinas
Descritor em inglês: Immunoglobulins
Descritor em espanhol: Inmunoglobulinas
Descritor inmunoglobulinas
Termo(s) alternativo(s) inmunoglobulina
Nota de escopo: Proteínas de múltiples subunidades que funcionan en la INMUNIDAD. Son producidas por los LINFOCITOS B a partir de los GENES DE LAS INMUNOGLOBULINAS. Están compuestos de dos cadenas pesadas y (CADENAS PESADAS DE LAS INMUNOGLOBULINAS) y de dos cadenas ligeras (CADENAS LIGERAS DE LAS INMUNOGLOBULINAS) con cadenas polipeptídicas secundarias adicionales dependiendo de sus isoformas. La variedad de isoformas incluye formas monoméricas o poliméricas y formas transmembranarias (RECEPTORES DE ANTÍGENOS DE LAS CÉLULAS B) o formas segregadas (ANTICUERPOS). Se dividen por la secuencia de aminoácidos de las cadenas pesadas en cinco clases (INMUNOGLOBULINA A, INMUNOGLOBULINA D, INMUNOGLOBULINA E, INMUNOGLOBULINA G, INMUNOGLOBULINA M) y varias subclases.
Descritor em francês: Immunoglobulines
Termo(s) alternativo(s): Globulin, Immune
Globulins, Immune
Immune Globulin
Immune Globulins
Immunoglobulin
Código(s) hierárquico(s): D12.776.124.486.485
D12.776.124.790.651
D12.776.377.715.548
Identificador Único RDF: https://id.nlm.nih.gov/mesh/D007136
Nota de escopo: Multi-subunit proteins which function in IMMUNITY. They are produced by B LYMPHOCYTES from the IMMUNOGLOBULIN GENES. They are comprised of two heavy (IMMUNOGLOBULIN HEAVY CHAINS) and two light chains (IMMUNOGLOBULIN LIGHT CHAINS) with additional ancillary polypeptide chains depending on their isoforms. The variety of isoforms include monomeric or polymeric forms, and transmembrane forms (B-CELL ANTIGEN RECEPTORS) or secreted forms (ANTIBODIES). They are divided by the amino acid sequence of their heavy chains into five classes (IMMUNOGLOBULIN A; IMMUNOGLOBULIN D; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M) and various subclasses.
Nota de indexação: general: prefer specifics; /admin: consider also IMMUNOGLOBULINS, INTRAVENOUS; /defic permitted but consider also IMMUNOLOGIC DEFICIENCY SYNDROMES ; /ther use: consider also IMMUNOGLOBULIN THERAPY see IMMUNIZATION, PASSIVE; allotypes = IMMUNOGLOBULIN ALLOTYPES or specifics
Qualificadores permitidos: AD administration & dosage
AE adverse effects
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PO poisoning
RE radiation effects
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Ação Farmacológica: Fatores Imunológicos
Indexação Anterior: Gamma Globulins (1966-1969)
Nota MeSH pública: 72; IMMUNE SERUM GLOBULIN was heading 1965; GLOBULINS, IMMUNE & IMMUNE GLOBULINS were see IMMUNOGLOBULINS, INTRAVENOUS 1992-93
Nota Online: use IMMUNOGLOBULINS, INTRAVENOUS to search GLOBULINS, IMMUNE& IMMUNE GLOBULINS 1992-93
Nota histórica: 72(70); IMMUNE SERUM GLOBULIN was heading 1965; GLOBULINS, IMMUNE & IMMUNE GLOBULINS were see IMMUNOGLOBULINS, INTRAVENOUS 1992-93
Veja também os descritores: Immunity MeSH
Paraproteinemias MeSH
Identificador DeCS: 22210
ID do descritor: D007136
Classificação da NLM: QW 601
Documentos indexados na Biblioteca Virtual em Saúde (BVS): Clique aqui para acessar os documentos da BVS
Data de estabelecimento: 01/01/1972
Data de entrada: 01/01/1999
Data de revisão: 27/05/2020
Immunoglobulins - Conceito preferido
Identificador do conceito M0011122
Nota de escopo Multi-subunit proteins which function in IMMUNITY. They are produced by B LYMPHOCYTES from the IMMUNOGLOBULIN GENES. They are comprised of two heavy (IMMUNOGLOBULIN HEAVY CHAINS) and two light chains (IMMUNOGLOBULIN LIGHT CHAINS) with additional ancillary polypeptide chains depending on their isoforms. The variety of isoforms include monomeric or polymeric forms, and transmembrane forms (B-CELL ANTIGEN RECEPTORS) or secreted forms (ANTIBODIES). They are divided by the amino acid sequence of their heavy chains into five classes (IMMUNOGLOBULIN A; IMMUNOGLOBULIN D; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M) and various subclasses.
Termo preferido Immunoglobulins
Termo(s) alternativo(s) Globulin, Immune
Globulins, Immune
Immune Globulin
Immune Globulins
Immunoglobulin



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