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Descritor em português: Fator Plaquetário 4
Descritor em inglês: Platelet Factor 4
Descritor em espanhol: Factor Plaquetario 4
Descritor factor plaquetario 4
Termo(s) alternativo(s) factor antiheparina
quimiocina CXCL4
Nota de escopo: Quimiocina CXC que se encuentra en los gránulos alfa de las PLAQUETAS. La proteína tiene un peso molecular de 7.800 kDa y puede presentarse como monómero, dímero o tetrámero dependiendo de su concentración en solución. El factor plaquetario 4 tiene gran afinidad por la HEPARINA y a menudo forma complejos con GLUCOPROTEÍNAS, como la PROTEÍNA C.
Descritor em francês: Facteur-4 plaquettaire
Termo(s) alternativo(s): Antiheparin Factor
CXCL4 Chemokine
CXCL4, Chemokine
Chemokine CXCL4
Chemokine, CXCL4
Heparin Neutralizing Protein
PF4 (Platelet Factor 4)
gamma Thromboglobulin
gamma-Thromboglobulin
Código(s) hierárquico(s): D12.644.276.374.200.120.900
D12.776.124.125.720
D12.776.467.374.200.120.900
D23.119.940
D23.125.300.120.900
D23.469.200.120.900
D23.529.374.200.120.900
Identificador Único RDF: https://id.nlm.nih.gov/mesh/D010978
Nota de escopo: A CXC chemokine that is found in the alpha granules of PLATELETS. The protein has a molecular size of 7800 kDa and can occur as a monomer, a dimer or a tetramer depending upon its concentration in solution. Platelet factor 4 has a high affinity for HEPARIN and is often found complexed with GLYCOPROTEINS such as PROTEIN C.
Qualificadores permitidos: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Ação Farmacológica: Coagulantes
Número de registro: 37270-94-3
Nome CAS Tipo 1: Blood platelet factor 4
Indexação Anterior: Blood Coagulation Factors (1973-1975)
Blood Platelets (1974-1975)
Glycoproteins (1974-1975)
Nota MeSH pública: 84; was see under BLOOD COAGULATION FACTORS 1976-83
Nota histórica: 84(76); was see under BLOOD COAGULATION FACTORS 1976-83
Identificador DeCS: 22259
ID do descritor: D010978
Documentos indexados na Biblioteca Virtual em Saúde (BVS): Clique aqui para acessar os documentos da BVS
Data de estabelecimento: 01/01/1984
Data de entrada: 25/07/1975
Data de revisão: 09/07/2007
Platelet Factor 4 - Conceito preferido
Identificador do conceito M0017019
Nota de escopo A CXC chemokine that is found in the alpha granules of PLATELETS. The protein has a molecular size of 7800 kDa and can occur as a monomer, a dimer or a tetramer depending upon its concentration in solution. Platelet factor 4 has a high affinity for HEPARIN and is often found complexed with GLYCOPROTEINS such as PROTEIN C.
Termo preferido Platelet Factor 4
Termo(s) alternativo(s) Antiheparin Factor
CXCL4 Chemokine
CXCL4, Chemokine
Chemokine CXCL4
Chemokine, CXCL4
Heparin Neutralizing Protein
PF4 (Platelet Factor 4)
gamma Thromboglobulin
gamma-Thromboglobulin



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