Visão selecionada em Inglês
| Descritor em português: | Fator D do Complemento | ||||||
| Descritor em inglês: | Complement Factor D | ||||||
| Descritor em espanhol: |
Factor D del Complemento
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| Descritor em francês: | Facteur D du complément | ||||||
| Termo(s) alternativo(s): |
28 kDa Protein, Adipocyte Activator, C3 Convertase Adipsin C3 Convertase Activator C3 Proactivator Convertase C3PA Convertase C3PAse Complement D Component Complement Protein D Convertase Activator, C3 Convertase, C3 Proactivator Convertase, C3PA Convertase, Proactivator D Component of Complement Factor D Factor D, Complement Factor D, Properdin GBGase Proactivator Convertase Properdin Factor D Protein D, Complement |
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| Código(s) hierárquico(s): |
D08.811.277.300.450 D08.811.277.656.300.760.200 D08.811.277.656.959.350.200 D12.776.124.486.274.045.450 |
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| Identificador Único RDF: | https://id.nlm.nih.gov/mesh/D011416 | ||||||
| Nota de escopo: | A serum protein which is important in the ALTERNATIVE COMPLEMENT ACTIVATION PATHWAY. This enzyme cleaves the COMPLEMENT C3B-bound COMPLEMENT FACTOR B to form C3bBb which is ALTERNATIVE PATHWAY C3 CONVERTASE. |
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| Nota de indexação: | see SCR for organism-specific terms |
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| Qualificadores permitidos: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Ação Farmacológica: |
Fatores Imunológicos |
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| Número de registro: | EC 3.4.21.46 | ||||||
| Indexação Anterior: |
Enzyme Precursors (1966-1977) Properdin (1966-1977) Serum Globulins (1970-1977) |
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| Nota MeSH pública: | 1999; see PROPERDIN FACTOR D 1991-1998, see COMPLEMENT ACTIVATING ENZYMES 1978-1990; ADIPSIN was indexed under SERINE ENDOPEPTIDASES 1987-2005 |
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| Nota histórica: | 1999 (1978) |
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| Identificador DeCS: | 23520 | ||||||
| ID do descritor: | D011416 | ||||||
| Documentos indexados na Biblioteca Virtual em Saúde (BVS): | Clique aqui para acessar os documentos da BVS | ||||||
| Data de estabelecimento: | 01/01/1991 | ||||||
| Data de entrada: | 20/05/1977 | ||||||
| Data de revisão: | 06/07/2009 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
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Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
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Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Complement Factor D
- Conceito preferido
| Identificador do conceito |
M0017753 |
| Nota de escopo | A serum protein which is important in the ALTERNATIVE COMPLEMENT ACTIVATION PATHWAY. This enzyme cleaves the COMPLEMENT C3B-bound COMPLEMENT FACTOR B to form C3bBb which is ALTERNATIVE PATHWAY C3 CONVERTASE. |
| Termo preferido | Complement Factor D |
| Termo(s) alternativo(s) |
28 kDa Protein, Adipocyte Activator, C3 Convertase Adipsin C3 Convertase Activator C3 Proactivator Convertase C3PA Convertase C3PAse Complement D Component Complement Protein D Convertase Activator, C3 Convertase, C3 Proactivator Convertase, C3PA Convertase, Proactivator D Component of Complement Factor D Factor D, Complement Factor D, Properdin GBGase Proactivator Convertase Properdin Factor D Protein D, Complement |
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