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Descritor em português: Enzimas de Restrição-Modificação do DNA
Descritor em inglês: DNA Restriction-Modification Enzymes
Descritor em espanhol: Enzimas de Restricción-Modificación del ADN
Descritor enzimas de restricción-modificación del ADN
Termo(s) alternativo(s) enzima de restricción y modificación del ADN
enzima de restricción-modificación del ADN
sistema de restricción y modificación
sistema de restricción-modificación
sistemas de restricción-modificación
Nota de escopo: Sistemas constituidos por dos enzimas, una metilasa de modificación y una endonucleasa de restricción. Están íntimamente relacionados en su especificidad y protegen el ADN de una determinada especie bacteriana. La metilasa añade grupos metilo a los residuos de adenina o citosina en la misma secuencia que constituye el sitio de unión de la enzima de restricción. La metilación hace que el sitio diana se vuelva resistente a la restricción, protegiendo así al ADN de la segmentación.
Descritor em francês: Enzymes de restriction-modification de l'ADN
Termo(s) alternativo(s): DNA Restriction Modification Enzyme
DNA Restriction Modification Enzymes
DNA Restriction-Modification Enzyme
Enzyme, DNA Restriction-Modification
Enzymes, DNA Restriction-Modification
Modification System, Restriction
Modification Systems, Restriction
Restriction Modification System
Restriction Modification Systems
Restriction-Modification Enzyme, DNA
Restriction-Modification Enzymes, DNA
Restriction-Modification System
Restriction-Modification Systems
System, Restriction Modification
System, Restriction-Modification
Systems, Restriction Modification
Systems, Restriction-Modification
Código(s) hierárquico(s): D08.811.150
Identificador Único RDF: https://id.nlm.nih.gov/mesh/D015280
Nota de escopo: Systems consisting of two enzymes, a modification methylase and a restriction endonuclease. They are closely related in their specificity and protect the DNA of a given bacterial species. The methylase adds methyl groups to adenine or cytosine residues in the same target sequence that constitutes the restriction enzyme binding site. The methylation renders the target site resistant to restriction, thereby protecting DNA against cleavage.
Qualificadores permitidos: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Indexação Anterior: DNA Restriction Enzymes (1975-1988)
Methyltransferases (1971-1988)
Nota MeSH pública: 89
Nota histórica: 89
Versão alternativa: RESTRICT MOD ENZYMES
Identificador DeCS: 23619
ID do descritor: D015280
Documentos indexados na Biblioteca Virtual em Saúde (BVS): Clique aqui para acessar os documentos da BVS
Data de estabelecimento: 01/01/1989
Data de entrada: 23/05/1988
Data de revisão: 27/05/2020
DNA Restriction-Modification Enzymes - Conceito preferido
Identificador do conceito M0023522
Nota de escopo Systems consisting of two enzymes, a modification methylase and a restriction endonuclease. They are closely related in their specificity and protect the DNA of a given bacterial species. The methylase adds methyl groups to adenine or cytosine residues in the same target sequence that constitutes the restriction enzyme binding site. The methylation renders the target site resistant to restriction, thereby protecting DNA against cleavage.
Termo preferido DNA Restriction-Modification Enzymes
Termo(s) alternativo(s) DNA Restriction Modification Enzyme
DNA Restriction Modification Enzymes
DNA Restriction-Modification Enzyme
Enzyme, DNA Restriction-Modification
Enzymes, DNA Restriction-Modification
Modification System, Restriction
Modification Systems, Restriction
Restriction Modification System
Restriction Modification Systems
Restriction-Modification Enzyme, DNA
Restriction-Modification Enzymes, DNA
Restriction-Modification System
Restriction-Modification Systems
System, Restriction Modification
System, Restriction-Modification
Systems, Restriction Modification
Systems, Restriction-Modification



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