Visão selecionada em Inglês
Descritor em português: | Transdução de Sinais | ||||||
Descritor em inglês: | Signal Transduction | ||||||
Descritor em espanhol: |
Transducción de Señal
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Descritor em francês: | Transduction du signal | ||||||
Termo(s) alternativo(s): |
Cell Signaling Pathway, Signal Pathway, Signal Transduction Pathways, Signal Pathways, Signal Transduction Receptor Mediated Signal Transduction Receptor-Mediated Signal Transduction Receptor-Mediated Signal Transductions Signal Pathway Signal Pathways Signal Transduction Pathway Signal Transduction Pathways Signal Transduction System Signal Transduction Systems Signal Transduction, Receptor-Mediated Signal Transductions Signal Transductions, Receptor-Mediated System, Signal Transduction Systems, Signal Transduction Transduction, Signal Transductions, Signal |
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Código(s) hierárquico(s): |
G02.111.820 G04.835 |
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Identificador Único RDF: | https://id.nlm.nih.gov/mesh/D015398 | ||||||
Nota de escopo: | The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway. |
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Qualificadores permitidos: |
DE drug effects GE genetics IM immunology PH physiology RE radiation effects |
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Indexação Anterior: |
Membrane Potentials (1977-1988) specific compounds/physiology (1977-1988) |
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Nota MeSH pública: | 89 |
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Nota histórica: | 89 |
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Veja também os descritores: |
Ion Channels
MeSH | ||||||
Identificador DeCS: | 23827 | ||||||
ID do descritor: | D015398 | ||||||
Classificação da NLM: | QU 375 | ||||||
Documentos indexados na Biblioteca Virtual em Saúde (BVS): | Clique aqui para acessar os documentos da BVS | ||||||
Data de estabelecimento: | 01/01/1989 | ||||||
Data de entrada: | 06/06/1988 | ||||||
Data de revisão: | 05/07/2019 |
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PHENOMENA AND PROCESSES
Chemical Phenomena [G02]Chemical Phenomena -
PHENOMENA AND PROCESSES
Cell Physiological Phenomena [G04]Cell Physiological Phenomena
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Signal Transduction
- Conceito preferido
Signal Pathways
- Mais específico
Signal Transduction Pathways
- Mais específico
Receptor-Mediated Signal Transduction
- Mais específico
Identificador do conceito |
M0023729 |
Nota de escopo | The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway. |
Termo preferido | Signal Transduction |
Termo(s) alternativo(s) |
Cell Signaling Signal Transduction System Signal Transduction Systems Signal Transductions System, Signal Transduction Systems, Signal Transduction Transduction, Signal Transductions, Signal |
Identificador do conceito |
M0023728 |
Termo preferido | Signal Pathways |
Termo(s) alternativo(s) |
Pathway, Signal Pathways, Signal Signal Pathway |
Identificador do conceito |
M0023730 |
Termo preferido | Signal Transduction Pathways |
Termo(s) alternativo(s) |
Pathway, Signal Transduction Pathways, Signal Transduction Signal Transduction Pathway |
Identificador do conceito |
M0023727 |
Termo preferido | Receptor-Mediated Signal Transduction |
Termo(s) alternativo(s) |
Receptor Mediated Signal Transduction Receptor-Mediated Signal Transductions Signal Transduction, Receptor-Mediated Signal Transductions, Receptor-Mediated |
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