Pesquisa
Descritor em português: Benserazida
Descritor em inglês: Benserazide
Descritor em espanhol: Benserazida
Descritor benseracida
Termo(s) alternativo(s) Ro 4-4602
seracida
seriltrihidroxibencilhidracina
Nota de escopo: Inhibidor de la DOPA DESCARBOXILASA que no penetra en el interior del sistema nervioso central. Se administra frecuentemente con LEVODOPA en el tratamiento del parkinsonismo para prevenir la conversión de levodopa a dopamina en la periferia, aumentando de este modo la cantidad que alcanza el sistema nervioso central y reduciendo la dosis requerida. No tiene acciones antiparkinsonianas cuando se administra solo.
Descritor em francês: Bensérazide
Termo(s) alternativo(s): Benzylhydrazine, Seryltrihydroxy
DL-Serine 2-((2,3,4-trihydroxyphenyl)methyl)hydrazide
Ro 4 4602
Ro 4-4602
Ro 44602
Serazide
Seryltrihydroxy Benzylhydrazine
Seryltrihydroxybenzylhydrazine
Código(s) hierárquico(s): D02.442.175
Identificador Único RDF: https://id.nlm.nih.gov/mesh/D001545
Nota de escopo: An inhibitor of DOPA DECARBOXYLASE that does not enter the central nervous system. It is often given with LEVODOPA in the treatment of parkinsonism to prevent the conversion of levodopa to dopamine in the periphery, thereby increasing the amount that reaches the central nervous system and reducing the required dose. It has no antiparkinson actions when given alone.
Qualificadores permitidos: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Ação Farmacológica: Antiparkinsonianos
Inibidores Enzimáticos
Dopaminérgicos
Número de registro: 762OS3ZEJU
Nome CAS Tipo 1: DL-Serine, 2-((2,3,4-trihydroxyphenyl)methyl)hydrazide
Indexação Anterior: Benzene (1966-1967)
Benzene Derivatives (1968-1971)
Benzyl Compounds (1972)
Hydrazines (1966-1972)
Serine (1966-1972)
Nota MeSH pública: 91; was see under HYDRAZINES 1979-90; was SERYLTRIHYDROXY BENZYLHYDRAZINE see under HYDRAZINES 1975-78
Nota Online: use BENSERAZIDE to search SERYLTRIHYDROXY BENZYLHYDRAZINE 1973-78 (as Prov 73-74)
Nota histórica: 91(79); was see under HYDRAZINES 1979-90; was SERYLTRIHYDROXY BENZYLHYDRAZINE see under HYDRAZINES 1973-78 (Prov 1973-74)
Identificador DeCS: 23953
ID do descritor: D001545
Documentos indexados na Biblioteca Virtual em Saúde (BVS): Clique aqui para acessar os documentos da BVS
Data de estabelecimento: 01/01/1991
Data de entrada: 01/01/1999
Data de revisão: 08/07/2013
Benserazide - Conceito preferido
Identificador do conceito M0002315
Nota de escopo An inhibitor of DOPA DECARBOXYLASE that does not enter the central nervous system. It is often given with LEVODOPA in the treatment of parkinsonism to prevent the conversion of levodopa to dopamine in the periphery, thereby increasing the amount that reaches the central nervous system and reducing the required dose. It has no antiparkinson actions when given alone.
Termo preferido Benserazide
Termo(s) alternativo(s) Benzylhydrazine, Seryltrihydroxy
DL-Serine 2-((2,3,4-trihydroxyphenyl)methyl)hydrazide
Serazide
Seryltrihydroxy Benzylhydrazine
Seryltrihydroxybenzylhydrazine
Ro 4-4602 - Mais específico
Identificador do conceito M0002316
Termo preferido Ro 4-4602
Termo(s) alternativo(s) Ro 4 4602
Ro 44602



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