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Descritor em português: Interferon gama
Descritor em inglês: Interferon-gamma
Descritor em espanhol: Interferón gamma
Descritor interferón gamma
Termo(s) alternativo(s) interferón inmunitario
Nota de escopo: El principal interferón producido por LINFOCITOS estimulados mitogénica o antigénicamente. Es estructuralmente diferente del INTERFERÓN TIPO I y su principal actividad es la inmunorregulación. Se ha relacionado con la expresión de ANTÍGENOS DE HISTOCOMPATIBILIDAD DE CLASE II en células que normalmente no los producen, dando lugar a ENFERMEDADES AUTOINMUNES.
Descritor em francês: Interféron gamma
Termo(s) alternativo(s): Immune Interferon
Interferon Type II
Interferon, Immune
Interferon, Type II
Interferon, gamma
Type II Interferon
gamma-Interferon
Código(s) hierárquico(s): D12.644.276.374.440.893
D12.644.276.374.480.615.350
D12.776.467.374.440.893
D12.776.467.374.480.615.350
D23.529.374.440.893
D23.529.374.480.615.350
Identificador Único RDF: https://id.nlm.nih.gov/mesh/D007371
Nota de escopo: The major interferon produced by mitogenically or antigenically stimulated LYMPHOCYTES. It is structurally different from TYPE I INTERFERON and its major activity is immunoregulation. It has been implicated in the expression of CLASS II HISTOCOMPATIBILITY ANTIGENS in cells that do not normally produce them, leading to AUTOIMMUNE DISEASES.
Qualificadores permitidos: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Ação Farmacológica: Antivirais
Número de registro: 82115-62-6
Nome CAS Tipo 1: Interferon gamma (human lymphocyte protein moiety reduced)
Indexação Anterior: Interferons (1966-1982)
Nota MeSH pública: 2009; see INTERFERON TYPE II 1984-2008, see INTERFERON, GAMMA 1983-1990
Nota histórica: 2009(1983); INTERFERON-GAMMA was INTERFERON, GAMMA 1983-1990
Veja também os descritores: Interferon-gamma Release Tests MeSH
Identificador DeCS: 29484
ID do descritor: D007371
Documentos indexados na Biblioteca Virtual em Saúde (BVS): Clique aqui para acessar os documentos da BVS
Data de estabelecimento: 01/01/1983
Data de entrada: 19/05/1982
Data de revisão: 22/06/2015
Interferon-gamma - Conceito preferido
Identificador do conceito M0011490
Nota de escopo The major interferon produced by mitogenically or antigenically stimulated LYMPHOCYTES. It is structurally different from TYPE I INTERFERON and its major activity is immunoregulation. It has been implicated in the expression of CLASS II HISTOCOMPATIBILITY ANTIGENS in cells that do not normally produce them, leading to AUTOIMMUNE DISEASES.
Termo preferido Interferon-gamma
Termo(s) alternativo(s) Immune Interferon
Interferon Type II
Interferon, Immune
Interferon, Type II
Interferon, gamma
Type II Interferon
gamma-Interferon



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