Pesquisa
Descritor em português: Apoptose
Descritor em inglês: Apoptosis
Descritor em espanhol: Apoptosis
Descritor apoptosis
Termo(s) alternativo(s) apoptosis clásica
apoptosis dependiente de caspasas
muerte celular programada
muerte celular programada de tipo I
vía extrínseca de la apoptosis
vía intrínseca de la apoptosis
Nota de escopo: Mecanismo de muerte celular regulada que se caracteriza por cambios morfológicos característicos en el núcleo y en el citoplasma, como la división endonucleótica del ADN genómico, en puntos internucleosómicos regularmente espaciados, es decir, FRAGMENTACIÓN DEL ADN. Está programado genéticamente y sirve como equilibrio para la mitosis en la regulación del tamaño de los tejidos animales y en la mediación de procesos patológicos asociados al crecimiento tumoral.
Descritor em francês: Apoptose
Termo(s) alternativo(s): Apoptoses, Extrinsic Pathway
Apoptoses, Intrinsic Pathway
Apoptosis, Caspase-Dependent
Apoptosis, Classic
Apoptosis, Classical
Apoptosis, Extrinsic Pathway
Apoptosis, Intrinsic Pathway
Caspase Dependent Apoptosis
Caspase-Dependent Apoptosis
Cell Death, Programmed
Classic Apoptoses
Classic Apoptosis
Classical Apoptosis
Extrinsic Pathway Apoptoses
Extrinsic Pathway Apoptosis
Intrinsic Pathway Apoptoses
Intrinsic Pathway Apoptosis
Programmed Cell Death
Programmed Cell Death, Type I
Código(s) hierárquico(s): G04.146.954.035
Identificador Único RDF: https://id.nlm.nih.gov/mesh/D017209
Nota de escopo: A regulated cell death mechanism characterized by distinctive morphologic changes in the nucleus and cytoplasm, including the endonucleolytic cleavage of genomic DNA, at regularly spaced, internucleosomal sites, i.e., DNA FRAGMENTATION. It is genetically programmed and serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth.
Nota de indexação: general or unspecified, note specifics
Qualificadores permitidos: DE drug effects
GE genetics
IM immunology
PH physiology
RE radiation effects
Indexação Anterior: Cell Survival (1972-1992)
Nota MeSH pública: 93
Nota histórica: 93
Veja também os descritores: CARD Signaling Adaptor Proteins MeSH
Caspases MeSH
Cellular Apoptosis Susceptibility Protein MeSH
Death Domain Receptor Signaling Adaptor Proteins MeSH
Genes, Transgenic, Suicide MeSH
In Situ Nick-End Labeling MeSH
Necrosis MeSH
Identificador DeCS: 30827
ID do descritor: D017209
Classificação da NLM: QU 375
Documentos indexados na Biblioteca Virtual em Saúde (BVS): Clique aqui para acessar os documentos da BVS
Data de estabelecimento: 01/01/1993
Data de entrada: 07/05/1992
Data de revisão: 09/06/2020
Apoptosis - Conceito preferido
Identificador do conceito M0026116
Nota de escopo A regulated cell death mechanism characterized by distinctive morphologic changes in the nucleus and cytoplasm, including the endonucleolytic cleavage of genomic DNA, at regularly spaced, internucleosomal sites, i.e., DNA FRAGMENTATION. It is genetically programmed and serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth.
Termo preferido Apoptosis
Termo(s) alternativo(s) Apoptosis, Classic
Apoptosis, Classical
Classic Apoptoses
Classic Apoptosis
Classical Apoptosis
Programmed Cell Death, Type I
Apoptosis, Intrinsic Pathway - Mais específico
Identificador do conceito M0493497
Nota de escopo A regulated cell death mechanism characterized by distinctive morphologic changes in the nucleus and cytoplasm, including the endonucleolytic cleavage of genomic DNA, at regularly spaced, internucleosomal sites, i.e., DNA FRAGMENTATION. It is genetically programmed and serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth.
Termo preferido Apoptosis, Intrinsic Pathway
Termo(s) alternativo(s) Apoptoses, Intrinsic Pathway
Intrinsic Pathway Apoptoses
Intrinsic Pathway Apoptosis
Apoptosis, Extrinsic Pathway - Mais específico
Identificador do conceito M0493496
Nota de escopo A regulated cell death mechanism characterized by distinctive morphologic changes in the nucleus and cytoplasm, including the endonucleolytic cleavage of genomic DNA, at regularly spaced, internucleosomal sites, i.e., DNA FRAGMENTATION. It is genetically programmed and serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth.
Termo preferido Apoptosis, Extrinsic Pathway
Termo(s) alternativo(s) Apoptoses, Extrinsic Pathway
Extrinsic Pathway Apoptoses
Extrinsic Pathway Apoptosis
Programmed Cell Death - Mais específico
Identificador do conceito M000644348
Nota de escopo A regulated cell death mechanism characterized by distinctive morphologic changes in the nucleus and cytoplasm, including the endonucleolytic cleavage of genomic DNA, at regularly spaced, internucleosomal sites, i.e., DNA FRAGMENTATION. It is genetically programmed and serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth.
Termo preferido Programmed Cell Death
Termo(s) alternativo(s) Cell Death, Programmed
Caspase-Dependent Apoptosis - Mais específico
Identificador do conceito M000675620
Termo preferido Caspase-Dependent Apoptosis
Termo(s) alternativo(s) Apoptosis, Caspase-Dependent
Caspase Dependent Apoptosis



Queremos a sua opinião sobre o novo sitio web do DeCS/MeSH

Convidamos-lhe a responder a uma pesquisa que não levará mais que 3 minutos

Ir para pesquisa