Pesquisa
Descritor em português: Deficiência de Proteína S
Descritor em inglês: Protein S Deficiency
Descritor em espanhol: Deficiencia de Proteína S
Descritor deficiencia de proteína S
Nota de escopo: Trastorno autosómico dominante que muestra niveles bajos del antígeno plasmático proteína S o de su actividad, se asocia con trombosis venosa y embolismo pulmonar. La PROTEÍNA S es una proteína plasmática que depende de la vitamina K, ésta inhibe la coagulación sanguínea al actuar como cofactor para la PROTEÍNA C activada (también una proteína dependiente de la vitamina K), y las manifestaciones clínicas de su déficit son virtualmente idénticas a las del déficit de proteína C. El tratamiento con heparina para los procesos trombóticos agudos usualmente se continúa con la administración de medicamentos cumarínicos para el mantenimiento, con el fin de prevenir la trombosis recurrente.
Descritor em francês: Déficit en protéine S
Termo(s) alternativo(s): Deficiencies, Protein S
Deficiency, Protein S
Hereditary Thrombophilia Due To Protein S Deficiency
Protein S Deficiencies
Código(s) hierárquico(s): C15.378.100.800
C15.378.147.890
C15.378.925.800
Identificador Único RDF: https://id.nlm.nih.gov/mesh/D018455
Nota de escopo: An autosomal dominant disorder showing decreased levels of plasma protein S antigen or activity, associated with venous thrombosis and pulmonary embolism. PROTEIN S is a vitamin K-dependent plasma protein that inhibits blood clotting by serving as a cofactor for activated PROTEIN C (also a vitamin K-dependent protein), and the clinical manifestations of its deficiency are virtually identical to those of protein C deficiency. Treatment with heparin for acute thrombotic processes is usually followed by maintenance administration of coumarin drugs for the prevention of recurrent thrombosis. (From Harrison's Principles of Internal Medicine, 12th ed, p1511; Wintrobe's Clinical Hematology, 9th ed, p1523)
Qualificadores permitidos: BL blood
CF cerebrospinal fluid
CI chemically induced
CL classification
CN congenital
CO complications
DG diagnostic imaging
DH diet therapy
DI diagnosis
DT drug therapy
EC economics
EH ethnology
EM embryology
EN enzymology
EP epidemiology
ET etiology
GE genetics
HI history
IM immunology
ME metabolism
MI microbiology
MO mortality
NU nursing
PA pathology
PC prevention & control
PP physiopathology
PS parasitology
PX psychology
RH rehabilitation
RT radiotherapy
SU surgery
TH therapy
UR urine
VE veterinary
VI virology
Indexação Anterior: Glycoproteins/deficiency (1984-1992)
Protein S/deficiency (1993-1994)
Nota MeSH pública: 95
Nota histórica: 95
Versão alternativa: PROTEIN S DEFIC
Identificador DeCS: 32063
ID do descritor: D018455
Documentos indexados na Biblioteca Virtual em Saúde (BVS): Clique aqui para acessar os documentos da BVS
Data de estabelecimento: 01/01/1995
Data de entrada: 16/04/1994
Data de revisão: 08/07/2013
Protein S Deficiency - Conceito preferido
Identificador do conceito M0027690
Nota de escopo An autosomal dominant disorder showing decreased levels of plasma protein S antigen or activity, associated with venous thrombosis and pulmonary embolism. PROTEIN S is a vitamin K-dependent plasma protein that inhibits blood clotting by serving as a cofactor for activated PROTEIN C (also a vitamin K-dependent protein), and the clinical manifestations of its deficiency are virtually identical to those of protein C deficiency. Treatment with heparin for acute thrombotic processes is usually followed by maintenance administration of coumarin drugs for the prevention of recurrent thrombosis. (From Harrison's Principles of Internal Medicine, 12th ed, p1511; Wintrobe's Clinical Hematology, 9th ed, p1523)
Termo preferido Protein S Deficiency
Termo(s) alternativo(s) Deficiencies, Protein S
Deficiency, Protein S
Hereditary Thrombophilia Due To Protein S Deficiency
Protein S Deficiencies



Queremos a sua opinião sobre o novo sitio web do DeCS/MeSH

Convidamos-lhe a responder a uma pesquisa que não levará mais que 3 minutos

Ir para pesquisa