DeCS

Descritor em português:

Mucina-1

Descritor em inglês:

Mucin-1

Descritor em espanhol:

Mucina-1

Espanhol da Espanha

Descritor	mucina 1
Termo(s) alternativo(s)	antígeno CA-15-3 antígeno de membrana epitelial episialina mucina Muc1 mucina epitelial polimórfica
Nota de escopo:	Antígeno carbohidrato que se halla aumentado en pacientes con tumores de mama, ovario, pulmones y próstata así como en otras enfermedades. La mucina se expresa normalmente en la mayoría de los epitelios glandulares, pero está especialmente aumentada en la mama durante la lactancia y en las neoplasias. Es, por tanto, un marcador sérico establecido para el cáncer de mama.

Descritor em francês:

Mucine-1

Termo(s) alternativo(s):

Antigen CA 15 3
Antigen CA-15-3
Antigen, CA 15-3
Antigen, CA 15.3
Antigen, CA-15-3
Antigen, CD227
Antigen, Epithelial Membrane
Antigens, CD227
CA 15 3 Antigen
CA 15-3 Antigen
CA 15.3 Antigen
CA-15-3 Antigen
CA-15-3, Antigen
CD227 Antigen
CD227 Antigens
Episialin
Epithelial Membrane Antigen
Epithelial Mucin, Polymorphic
Membrane Antigen, Epithelial
Muc1 Mucin
Mucin 1
Mucin, Muc1
Mucin, Polymorphic Epithelial
Polymorphic Epithelial Mucin

Código(s) hierárquico(s):

D09.400.430.890.560
D09.400.430.900.631.115
D12.776.395.550.560
D12.776.395.560.631.115
D12.776.543.550.530
D23.050.285.050.300
D23.050.550.325.300
D23.101.140.075.300

Identificador Único RDF:

https://id.nlm.nih.gov/mesh/D018396

Nota de escopo:

Carbohydrate antigen elevated in patients with tumors of the breast, ovary, lung, and prostate as well as other disorders. The mucin is expressed normally by most glandular epithelia but shows particularly increased expression in the breast at lactation and in malignancy. It is thus an established serum marker for breast cancer.

Qualificadores permitidos:

AD administration & dosage
AE adverse effects
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
DE drug effects
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PO poisoning
RE radiation effects
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine

Indexação Anterior:

Antigens, Neoplasm (1986-1988)
Antigens, Tumor-Associated, Carbohydrate (1989-1994)

Nota MeSH pública:

2009; see CA-15-3 ANTIGEN 1995-2008, see ANTIGENS, TUMOR-ASSOCIATED, CARBOHYDRATE 1990-1994; EPISIALIN was indexed under MEMBRANE GLYCOPROTEINS 1988-1996, MUCINS 1981-1996, MEMBRANE PROTEINS 1982-1987, & GLYCOPROTEINS 1981-1982

Identificador do conceito	M0027622
Nota de escopo	Carbohydrate antigen elevated in patients with tumors of the breast, ovary, lung, and prostate as well as other disorders. The mucin is expressed normally by most glandular epithelia but shows particularly increased expression in the breast at lactation and in malignancy. It is thus an established serum marker for breast cancer.
Termo preferido	Mucin-1
Termo(s) alternativo(s)	Antigen CA 15 3 Antigen CA-15-3 Antigen, CA 15-3 Antigen, CA 15.3 Antigen, CA-15-3 Antigen, CD227 Antigen, Epithelial Membrane Antigens, CD227 CA 15 3 Antigen CA 15-3 Antigen CA 15.3 Antigen CA-15-3 Antigen CA-15-3, Antigen CD227 Antigen CD227 Antigens Episialin Epithelial Membrane Antigen Epithelial Mucin, Polymorphic Membrane Antigen, Epithelial Muc1 Mucin Mucin 1 Mucin, Muc1 Mucin, Polymorphic Epithelial Polymorphic Epithelial Mucin

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