Visão selecionada em Inglês
| Descritor em português: | Pró-Proteína Convertase 1 | ||||||
| Descritor em inglês: | Proprotein Convertase 1 | ||||||
| Descritor em espanhol: |
Proproteína Convertasa 1
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| Descritor em francês: | Proprotein convertase 1 | ||||||
| Termo(s) alternativo(s): |
Convertase 1, Proprotein Convertase PC1, Neuroendocrine Convertase SPC3, Proprotein Convertase, PC1 Prohormone Convertase, PC3 Prohormone Endoprotease, PC1 Endoprotease, PC3 Neuroendocrine Convertase PC1 PC1 Endoprotease PC1 Prohormone Convertase PC3 Endoprotease PC3 Prohormone Convertase Prohormone Convertase 1 Prohormone Convertase 3 Prohormone Convertase, PC1 Prohormone Convertase, PC3 Proinsulin Convertase 1 Proprotein Convertase SPC3 |
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| Código(s) hierárquico(s): |
D08.811.277.656.300.760.640 D08.811.277.656.837.500 D08.811.277.656.959.350.640 |
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| Identificador Único RDF: | https://id.nlm.nih.gov/mesh/D045664 | ||||||
| Nota de escopo: | A CALCIUM-dependent endopeptidase that has specificity for cleavage at ARGININE that is near paired basic residues. It cleaves a variety of prohormones including PRO-OPIOMELANOCORTIN; PRORENIN; proenkephalins; prodynorphin; prosomatostatin; and PROINSULIN. |
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| Qualificadores permitidos: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Número de registro: | EC 3.4.21.93 | ||||||
| Indexação Anterior: |
Aspartic Endopeptidases (1991-2003) |
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| Nota MeSH pública: | 2004; PC1 PROHORMONE CONVERTASE, NEUROENDOCRINE CONVERTASE PC1, PC3 ENDOPROTEASE & PROHORMONE CONVERTASE 1 were indexed under ASPARTIC ENDOPEPTIDASES 1991-2003; PC1 ENDOPROTEASE & PC3 PROHORMONE CONVERTASE were indexed under ASPARTIC ENDOPEPTIDASES 1993-2003; PROPROTEIN CONVERTASE SPC3 was indexed under ASPARTIC ENDOPEPTIDASES 2001-2003; PROINSULIN CONVERTASE 1 was indexed under ASPARTIC ENDOPEPTIDASES 2002-2003; |
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| Nota histórica: | 2004; for PC1 PROHORMONE CONVERTASE, NEUROENDOCRINE CONVERTASE PC1, PC3 ENDOPROTEASE, PROHORMONE CONVERTASE 1 use PROPROTEIN CONVERTASE (NM) 1991-2003; for PC1 ENDOPROTEASE & PC3 PROHORMONE CONVERTASE use PROPROTEIN CONVERTASE (NM) 1993-2003; for PROPROTEIN CONVERTASE SPC3 use PROPROTEIN CONVERTASE (NM) 2001-2003; for PROINSULIN CONVERTASE 1 use PROPROTEIN CONVERTASE (NM) 2002-2003 |
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| Identificador DeCS: | 38169 | ||||||
| ID do descritor: | D045664 | ||||||
| Documentos indexados na Biblioteca Virtual em Saúde (BVS): | Clique aqui para acessar os documentos da BVS | ||||||
| Data de estabelecimento: | 01/01/2004 | ||||||
| Data de entrada: | 09/07/2003 | ||||||
| Data de revisão: | 06/07/2009 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes
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Proprotein Convertase 1
- Conceito preferido
| Identificador do conceito |
M0103931 |
| Nota de escopo | A CALCIUM-dependent endopeptidase that has specificity for cleavage at ARGININE that is near paired basic residues. It cleaves a variety of prohormones including PRO-OPIOMELANOCORTIN; PRORENIN; proenkephalins; prodynorphin; prosomatostatin; and PROINSULIN. |
| Termo preferido | Proprotein Convertase 1 |
| Termo(s) alternativo(s) |
Convertase 1, Proprotein Convertase PC1, Neuroendocrine Convertase SPC3, Proprotein Convertase, PC1 Prohormone Convertase, PC3 Prohormone Endoprotease, PC1 Endoprotease, PC3 Neuroendocrine Convertase PC1 PC1 Endoprotease PC1 Prohormone Convertase PC3 Endoprotease PC3 Prohormone Convertase Prohormone Convertase 1 Prohormone Convertase 3 Prohormone Convertase, PC1 Prohormone Convertase, PC3 Proinsulin Convertase 1 Proprotein Convertase SPC3 |
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