Pesquisa
Descritor em português: Ligante 4-1BB
Descritor em inglês: 4-1BB Ligand
Descritor em espanhol: Ligando 4-1BB
Descritor ligando 4-1BB
Termo(s) alternativo(s) miembro 9 de la superfamilia de ligandos del factor de necrosis tumoral
Nota de escopo: Miembro unido a la membrana de la superfamilia del FNT que se expresa en los LINFOCITOS B activados, MACRÓFAGOS y CÉLULAS DENDRÍTICAS. El ligando es específico para el RECEPTOR 4-1BB y puede desempeñar un papel en la indución de la proliferación de los LINFOCITOS T activados de la sangre periférica.
Descritor em francês: Ligand de 4-1BB
Termo(s) alternativo(s): 4 1BB Ligand
4 1BBL Protein
4-1BBL Protein
CD137 Ligand
Tumor Necrosis Factor (Ligand) Superfamily, Member 9
Tumor Necrosis Factor Ligand Superfamily Member 9
Código(s) hierárquico(s): D12.644.276.374.750.065
D12.776.395.192
D12.776.467.374.750.065
D12.776.543.550.194
D23.529.374.750.065
Identificador Único RDF: https://id.nlm.nih.gov/mesh/D053330
Nota de escopo: A membrane bound member of the TNF superfamily that is expressed on activated B-LYMPHOCYTES; MACROPHAGES; and DENDRITIC CELLS. The ligand is specific for the 4-1BB RECEPTOR and may play a role in inducing the proliferation of activated peripheral blood T-LYMPHOCYTES.
Qualificadores permitidos: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Nota MeSH pública: 2007; 4-1BB LIGAND was indexed under TUMOR NECROSIS FACTORS 2006 & under TUMOR NECROSIS FACTOR-ALPHA 1998-2005
Nota histórica: 2007(1998)
Identificador DeCS: 52290
ID do descritor: D053330
Documentos indexados na Biblioteca Virtual em Saúde (BVS): Clique aqui para acessar os documentos da BVS
Data de estabelecimento: 01/01/2007
Data de entrada: 05/07/2006
Data de revisão: 22/06/2015
4-1BB Ligand - Conceito preferido
Identificador do conceito M0291679
Nota de escopo A membrane bound member of the TNF superfamily that is expressed on activated B-LYMPHOCYTES; MACROPHAGES; and DENDRITIC CELLS. The ligand is specific for the 4-1BB RECEPTOR and may play a role in inducing the proliferation of activated peripheral blood T-LYMPHOCYTES.
Termo preferido 4-1BB Ligand
Termo(s) alternativo(s) 4 1BB Ligand
4 1BBL Protein
4-1BBL Protein
CD137 Ligand
Tumor Necrosis Factor (Ligand) Superfamily, Member 9
Tumor Necrosis Factor Ligand Superfamily Member 9



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