Pesquisa
Descritor em português: Osteoprotegerina
Descritor em inglês: Osteoprotegerin
Descritor em espanhol: Osteoprotegerina
Descritor osteoprotegerina
Termo(s) alternativo(s) factor inhibidor de osteoclastogénesis
miembro 11b de la superfamilia de receptores del factor de necrosis tumoral
miembro 11b de los receptores de factores de necrosis tumoral
miembro 11b de los receptores del factor de necrosis tumoral
Nota de escopo: Miembro secretado de la superfamilia de receptores de TNF que regula negativamente la osteoclastogénesis. Es un receptor señuelo soluble del LIGANDO RANK que inhibe tanto la DIFERENCIACIÓN CELULAR como la función de los OSTEOCLASTOS, inhibiendo la interacción entre el LIGANDO RANK y el ACTIVADOR DEL RECEPTOR DEL FACTOR NUCLEAR-KAPPA B.
Descritor em francês: Ostéoprotégérine
Termo(s) alternativo(s): FDCR 1 Protein
FDCR-1 Protein
Follicular Dendritic Cell Derived Receptor 1
Follicular Dendritic Cell-Derived Receptor-1
OCIF Protein
Osteoclastogenesis Inhibitory Factor
Receptors, Tumor Necrosis Factor, Member 11b
Tumor Necrosis Factor Receptor 11b
Tumor Necrosis Factor Receptor Superfamily, Member 11b
Código(s) hierárquico(s): D12.776.543.750.705.852.760.949.249
Identificador Único RDF: https://id.nlm.nih.gov/mesh/D053244
Nota de escopo: A secreted member of the TNF receptor superfamily that negatively regulates osteoclastogenesis. It is a soluble decoy receptor of RANK LIGAND that inhibits both CELL DIFFERENTIATION and function of OSTEOCLASTS by inhibiting the interaction between RANK LIGAND and RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B.
Qualificadores permitidos: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Nota MeSH pública: 2007; OSTEOPROTEGERIN was indexed under RECEPTORS, TUMOR NECROSIS FACTOR, RECEPTORS, CYTOPLASMIC AND NUCLEAR & GLYCOPROTEINS 1997-2006
Nota histórica: 2007(1997)
Identificador DeCS: 52396
ID do descritor: D053244
Documentos indexados na Biblioteca Virtual em Saúde (BVS): Clique aqui para acessar os documentos da BVS
Data de estabelecimento: 01/01/2007
Data de entrada: 05/07/2006
Osteoprotegerin - Conceito preferido
Identificador do conceito M0275318
Nota de escopo A secreted member of the TNF receptor superfamily that negatively regulates osteoclastogenesis. It is a soluble decoy receptor of RANK LIGAND that inhibits both CELL DIFFERENTIATION and function of OSTEOCLASTS by inhibiting the interaction between RANK LIGAND and RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B.
Termo preferido Osteoprotegerin
Termo(s) alternativo(s) FDCR 1 Protein
FDCR-1 Protein
Follicular Dendritic Cell Derived Receptor 1
Follicular Dendritic Cell-Derived Receptor-1
OCIF Protein
Osteoclastogenesis Inhibitory Factor
Receptors, Tumor Necrosis Factor, Member 11b
Tumor Necrosis Factor Receptor 11b
Tumor Necrosis Factor Receptor Superfamily, Member 11b



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