Visão selecionada em Inglês
Descritor em português: | Endonuclease PMS2 de Reparo de Erro de Pareamento | ||||||
Descritor em inglês: | Mismatch Repair Endonuclease PMS2 | ||||||
Descritor em espanhol: |
Endonucleasa PMS2 de Reparación del Emparejamiento Incorrecto
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Descritor em francês: | Mismatch repair endonuclease PMS2 | ||||||
Termo(s) alternativo(s): |
PMS 2 Protein PMS-2 Protein PMS1 Homolog 2, Mismatch Repair Protein PMS2 Protein Postmeiotic Segregation Increased S. cerevisiae 2 Postmeiotic Segregation Increased-S. cerevisiae-2 |
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Código(s) hierárquico(s): |
D08.811.074.766.250 D08.811.277.040.025.215.250 D08.811.277.352.335.350.600 D12.776.260.540.250 |
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Identificador Único RDF: | https://id.nlm.nih.gov/mesh/D000070976 | ||||||
Nota de escopo: | A MutL protein and component of the DNA MISMATCH REPAIR system. Its ENDONUCLEASE activity introduces SINGLE-STRAND DNA BREAKS which create entry points for EXO1 exonuclease to remove the strand containing the mismatch. It may also function in DNA DAMAGE signaling. |
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Qualificadores permitidos: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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Número de registro: | EC 3.6.1.3 | ||||||
Indexação Anterior: |
Adenosine Triphosphatases (2001-2016) DNA Repair Enzymes (2001-2016) |
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Nota MeSH pública: | 2017 |
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Nota histórica: | 2017 |
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Identificador DeCS: | 56466 | ||||||
ID do descritor: | D000070976 | ||||||
Documentos indexados na Biblioteca Virtual em Saúde (BVS): | Clique aqui para acessar os documentos da BVS | ||||||
Data de estabelecimento: | 01/01/2017 | ||||||
Data de entrada: | 08/07/2016 | ||||||
Data de revisão: | 01/03/2016 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Mismatch Repair Endonuclease PMS2
- Conceito preferido
Identificador do conceito |
M000612774 |
Nota de escopo | A MutL protein and component of the DNA MISMATCH REPAIR system. Its ENDONUCLEASE activity introduces SINGLE-STRAND DNA BREAKS which create entry points for EXO1 exonuclease to remove the strand containing the mismatch. It may also function in DNA DAMAGE signaling. |
Termo preferido | Mismatch Repair Endonuclease PMS2 |
Termo(s) alternativo(s) |
PMS 2 Protein PMS-2 Protein PMS1 Homolog 2, Mismatch Repair Protein PMS2 Protein Postmeiotic Segregation Increased S. cerevisiae 2 Postmeiotic Segregation Increased-S. cerevisiae-2 |
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