Visão selecionada em Inglês
| Descritor em português: | Perilipinas | ||||||
| Descritor em inglês: | Perilipins | ||||||
| Descritor em espanhol: |
Perilipinas
| ||||||
| Descritor em francês: | Périlipines | ||||||
| Termo(s) alternativo(s): |
PAT Proteins PLIN Proteins Perilipin Adipophilin TIP47 Proteins Perilipin Proteins Perilipin-Adipophilin-TIP47 Proteins Proteins, PAT Proteins, PLIN Proteins, Perilipin Proteins, Perilipin-Adipophilin-TIP47 |
||||||
| Código(s) hierárquico(s): |
D12.776.157.464.500 |
||||||
| Identificador Único RDF: | https://id.nlm.nih.gov/mesh/D000070137 | ||||||
| Nota de escopo: | A family of vertebrate and insect lipid droplet associated proteins. They consist of a conserved N-terminal PAT domain (an alpha-helical region of about 110 amino acids), an 11-mer repeat region, and lipid-binding hydrophobic regions or 4-helix bundles near their C-termini. Perilipins transiently or constitutively localize to LIPID DROPLETS in ADIPOCYTES and FOAM CELLS, especially in regions adjacent to the PLASMA MEMBRANE and ENDOPLASMIC RECTICULUM. They are critical for lipid droplet synthesis and homeostasis as well as the regulation of lipid metabolism. Genetic variations in perilipins are associated with ATHEROSCLEROSIS; OBESITY; and DIABETES MELLITUS. |
||||||
| Qualificadores permitidos: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
||||||
| Indexação Anterior: |
Carrier Proteins (1991-2016) |
||||||
| Nota MeSH pública: | 2017 |
||||||
| Nota histórica: | 2017 |
||||||
| Identificador DeCS: | 56570 | ||||||
| ID do descritor: | D000070137 | ||||||
| Documentos indexados na Biblioteca Virtual em Saúde (BVS): | Clique aqui para acessar os documentos da BVS | ||||||
| Data de estabelecimento: | 01/01/2017 | ||||||
| Data de entrada: | 08/07/2016 | ||||||
| Data de revisão: | 19/01/2016 |
-
-
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
|
|
Perilipins
- Conceito preferido
| Identificador do conceito |
M000609416 |
| Nota de escopo | A family of vertebrate and insect lipid droplet associated proteins. They consist of a conserved N-terminal PAT domain (an alpha-helical region of about 110 amino acids), an 11-mer repeat region, and lipid-binding hydrophobic regions or 4-helix bundles near their C-termini. Perilipins transiently or constitutively localize to LIPID DROPLETS in ADIPOCYTES and FOAM CELLS, especially in regions adjacent to the PLASMA MEMBRANE and ENDOPLASMIC RECTICULUM. They are critical for lipid droplet synthesis and homeostasis as well as the regulation of lipid metabolism. Genetic variations in perilipins are associated with ATHEROSCLEROSIS; OBESITY; and DIABETES MELLITUS. |
| Termo preferido | Perilipins |
| Termo(s) alternativo(s) |
PAT Proteins PLIN Proteins Perilipin Adipophilin TIP47 Proteins Perilipin Proteins Perilipin-Adipophilin-TIP47 Proteins Proteins, PAT Proteins, PLIN Proteins, Perilipin Proteins, Perilipin-Adipophilin-TIP47 |
Queremos a sua opinião sobre o novo sitio web do DeCS/MeSH
Convidamos-lhe a responder a uma pesquisa que não levará mais que 3 minutos
Ir para pesquisa
