Visão selecionada em Inglês
| Descritor em português: | Proteína 1 Homóloga a Discs-Large | ||||||
| Descritor em inglês: | Discs Large Homolog 1 Protein | ||||||
| Descritor em espanhol: |
Homólogo 1 de la Proteína Discs Large
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| Descritor em francês: | Homologue-1 de la protéine Discs Large | ||||||
| Termo(s) alternativo(s): |
Synapse Associated Protein 97 Synapse-Associated Protein 97 |
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| Código(s) hierárquico(s): |
D08.811.913.696.650.450.500 D12.644.360.024.287 D12.776.157.057.023 D12.776.476.024.325 D12.776.543.213 |
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| Identificador Único RDF: | https://id.nlm.nih.gov/mesh/D000074288 | ||||||
| Nota de escopo: | A signaling adaptor protein that contains three PDZ DOMAINS; an SH3 DOMAIN; and a GUANYLATE KINASE-like C-terminal region. It has an essential role in animal development and recruits ion channels, receptors, and signaling molecules to discrete plasma membrane regions of polarized cells in the HEART ATRIA MYOCARDIUM. It functions in the assembly of ADHERENS JUNCTIONS and regulation of CELL PROLIFERATION; synaptogenesis, LYMPHOCYTE ACTIVATION; and controls expression of KV4 POTASSIUM CHANNELS to regulate excitability of CARDIAC MYOCYTES. |
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| Qualificadores permitidos: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Indexação Anterior: |
Adaptor Proteins, Signal Transducing (2006-2017) Membrane Proteins (2006-2017) |
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| Nota MeSH pública: | 2018 |
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| Nota histórica: | 2018 |
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| Identificador DeCS: | 57035 | ||||||
| ID do descritor: | D000074288 | ||||||
| Documentos indexados na Biblioteca Virtual em Saúde (BVS): | Clique aqui para acessar os documentos da BVS | ||||||
| Data de estabelecimento: | 01/01/2018 | ||||||
| Data de entrada: | 11/07/2017 | ||||||
| Data de revisão: | 27/02/2017 |
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CHEMICALS AND DRUGS
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Discs Large Homolog 1 Protein
- Conceito preferido
| Identificador do conceito |
M000625934 |
| Nota de escopo | A signaling adaptor protein that contains three PDZ DOMAINS; an SH3 DOMAIN; and a GUANYLATE KINASE-like C-terminal region. It has an essential role in animal development and recruits ion channels, receptors, and signaling molecules to discrete plasma membrane regions of polarized cells in the HEART ATRIA MYOCARDIUM. It functions in the assembly of ADHERENS JUNCTIONS and regulation of CELL PROLIFERATION; synaptogenesis, LYMPHOCYTE ACTIVATION; and controls expression of KV4 POTASSIUM CHANNELS to regulate excitability of CARDIAC MYOCYTES. |
| Termo preferido | Discs Large Homolog 1 Protein |
| Termo(s) alternativo(s) |
Synapse Associated Protein 97 Synapse-Associated Protein 97 |
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