Visão selecionada em Inglês
| Descritor em português: | 5-Aminolevulinato Sintetase | ||||||
| Descritor em inglês: | 5-Aminolevulinate Synthetase | ||||||
| Descritor em espanhol: |
5-Aminolevulinato Sintetasa
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| Descritor em francês: | 5-Aminolevulinate synthetase | ||||||
| Termo(s) alternativo(s): |
5 Aminolevulinate Synthase 5 Aminolevulinate Synthetase 5-Aminolevulinate Synthase Acid Synthetase, Aminolevulinic Acid Synthetase, delta-Aminolevulinic Aminolevulinic Acid Synthetase Synthase, 5-Aminolevulinate Synthase, delta-Aminolevulinate Synthetase, 5-Aminolevulinate Synthetase, Aminolevulinic Acid Synthetase, delta-Aminolevulinic Acid delta Aminolevulinate Synthase delta Aminolevulinic Acid Synthetase delta-Aminolevulinate Synthase delta-Aminolevulinic Acid Synthetase |
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| Código(s) hierárquico(s): |
D08.811.913.050.276 |
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| Identificador Único RDF: | https://id.nlm.nih.gov/mesh/D000624 | ||||||
| Nota de escopo: | An enzyme of the transferase class that catalyzes condensation of the succinyl group from succinyl coenzyme A with glycine to form delta-aminolevulinate. It is a pyridoxyal phosphate protein and the reaction occurs in mitochondria as the first step of the heme biosynthetic pathway. The enzyme is a key regulatory enzyme in heme biosynthesis. In liver feedback is inhibited by heme. EC 2.3.1.37. |
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| Qualificadores permitidos: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Número de registro: | EC 2.3.1.37 | ||||||
| Nome CAS Tipo 1: | Succinyl-CoA:glycine C-Succinyltransferase (decarboxylating) | ||||||
| Indexação Anterior: |
Acyltransferases (1966-1971) |
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| Nota MeSH pública: | 98; see AMINOLEVULINIC ACID SYNTHETASE 1972-97 |
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| Nota histórica: | 98(72) |
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| Identificador DeCS: | 634 | ||||||
| ID do descritor: | D000624 | ||||||
| Documentos indexados na Biblioteca Virtual em Saúde (BVS): | Clique aqui para acessar os documentos da BVS | ||||||
| Data de estabelecimento: | 01/01/1973 | ||||||
| Data de entrada: | 01/01/1999 | ||||||
| Data de revisão: | 09/07/2007 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes
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5-Aminolevulinate Synthetase
- Conceito preferido
| Identificador do conceito |
M0000954 |
| Nota de escopo | An enzyme of the transferase class that catalyzes condensation of the succinyl group from succinyl coenzyme A with glycine to form delta-aminolevulinate. It is a pyridoxyal phosphate protein and the reaction occurs in mitochondria as the first step of the heme biosynthetic pathway. The enzyme is a key regulatory enzyme in heme biosynthesis. In liver feedback is inhibited by heme. EC 2.3.1.37. |
| Termo preferido | 5-Aminolevulinate Synthetase |
| Termo(s) alternativo(s) |
5 Aminolevulinate Synthase 5 Aminolevulinate Synthetase 5-Aminolevulinate Synthase Acid Synthetase, Aminolevulinic Acid Synthetase, delta-Aminolevulinic Aminolevulinic Acid Synthetase Synthase, 5-Aminolevulinate Synthase, delta-Aminolevulinate Synthetase, 5-Aminolevulinate Synthetase, Aminolevulinic Acid Synthetase, delta-Aminolevulinic Acid delta Aminolevulinate Synthase delta Aminolevulinic Acid Synthetase delta-Aminolevulinate Synthase delta-Aminolevulinic Acid Synthetase |
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