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Descritor em português: Oxigenases de Função Mista
Descritor em inglês: Mixed Function Oxygenases
Descritor em espanhol: Oxigenasas de Función Mixta
Descritor oxigenasas de función múltiple
Termo(s) alternativo(s) hidroxilasa
hidroxilasas
monooxigenasa
monooxigenasas
oxidasa de función mixta
oxigenasa de función mixta
Nota de escopo: Enzimas ampliamente distribuidas que llevan a cabo las reacciones de oxidación-reducción en las que un átomo de la molécula de oxigeno es incorporada al sustrato orgánico; el otro átomo de oxigeno es reducido y combinado con iones de hidrógeno para formar agua. También se conocen como monooxigenasas o hidroxilasas. Esas reacciones requieren dos sustratos como reductores de cada uno de los dos átomos de oxigeno. Hay distintas clases de monooxigenasas según el tipo de co-sustrato suministrador de hidrógeno (COENZIMAS) utilizado en la oxidación.
Descritor em francês: Mixed function oxygenases
Termo(s) alternativo(s): Function Oxidase, Mixed
Function Oxygenase, Mixed
Hydroxylase
Hydroxylases
Mixed Function Oxidase
Mixed Function Oxidases
Mixed Function Oxygenase
Monooxygenase
Monooxygenases
Oxidase, Mixed Function
Oxidases, Mixed Function
Oxygenase, Mixed Function
Oxygenases, Mixed Function
Código(s) hierárquico(s): D08.811.682.690.708
Identificador Único RDF: https://id.nlm.nih.gov/mesh/D006899
Nota de escopo: Widely distributed enzymes that carry out oxidation-reduction reactions in which one atom of the oxygen molecule is incorporated into the organic substrate; the other oxygen atom is reduced and combined with hydrogen ions to form water. They are also known as monooxygenases or hydroxylases. These reactions require two substrates as reductants for each of the two oxygen atoms. There are different classes of monooxygenases depending on the type of hydrogen-providing cosubstrate (COENZYMES) required in the mixed-function oxidation.
Nota de indexação: do not confuse with HYDRO-LYASES
Qualificadores permitidos: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Número de registro: EC 1.-
Nota MeSH pública: 2003 (1966)
Nota histórica: 2003 (1966)
Identificador DeCS: 7067
ID do descritor: D006899
Classificação da NLM: QU 140
Documentos indexados na Biblioteca Virtual em Saúde (BVS): Clique aqui para acessar os documentos da BVS
Data de estabelecimento: 01/01/2003
Data de entrada: 01/01/1999
Data de revisão: 27/05/2020
Mixed Function Oxygenases - Conceito preferido
Identificador do conceito M0010768
Nota de escopo Widely distributed enzymes that carry out oxidation-reduction reactions in which one atom of the oxygen molecule is incorporated into the organic substrate; the other oxygen atom is reduced and combined with hydrogen ions to form water. They are also known as monooxygenases or hydroxylases. These reactions require two substrates as reductants for each of the two oxygen atoms. There are different classes of monooxygenases depending on the type of hydrogen-providing cosubstrate (COENZYMES) required in the mixed-function oxidation.
Termo preferido Mixed Function Oxygenases
Termo(s) alternativo(s) Function Oxidase, Mixed
Function Oxygenase, Mixed
Hydroxylase
Hydroxylases
Mixed Function Oxidase
Mixed Function Oxidases
Mixed Function Oxygenase
Monooxygenase
Monooxygenases
Oxidase, Mixed Function
Oxidases, Mixed Function
Oxygenase, Mixed Function
Oxygenases, Mixed Function



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