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Descritor em português: | 2-Isopropilmalato Sintase | ||||
Descritor em inglês: | 2-Isopropylmalate Synthase | ||||
Descritor em espanhol: |
2-Isopropilmalato Sintasa
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Descritor em francês: | 2-Isopropylmalate synthase | ||||
Termo(s) alternativo(s): |
2 Isopropylmalate Synthase Synthase, 2-Isopropylmalate Synthase, alpha-Isopropylmalate alpha Isopropylmalate Synthase alpha-Isopropylmalate Synthase |
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Código(s) hierárquico(s): |
D08.811.913.050.614 |
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Identificador Único RDF: | https://id.nlm.nih.gov/mesh/D015079 | ||||
Nota de escopo: | An enzyme that catalyzes the first step in the biosynthetic pathway to LEUCINE, forming isopropyl malate from acetyl-CoA and alpha-ketoisovaleric acid. This enzyme was formerly listed as EC 4.1.3.12. |
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Qualificadores permitidos: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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Número de registro: | EC 2.3.3.13 | ||||
Nome CAS Tipo 1: | 3-Carboxy-3-hydroxy-4-methylpentanoate 3-methyl-2-oxobutanoate-lyase (CoA-acetylating) | ||||
Indexação Anterior: |
Ketoacid-Lyases (1973-1974) Ketoacids (1973-1974) Malates (1973-1974) |
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Nota MeSH pública: | 91; was see under KETOACID-LYASES 1975-90 |
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Nota histórica: | 91(75); was see under KETOACID-LYASES 1975-90 |
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Identificador DeCS: | 7712 | ||||
ID do descritor: | D015079 | ||||
Documentos indexados na Biblioteca Virtual em Saúde (BVS): | Clique aqui para acessar os documentos da BVS | ||||
Data de estabelecimento: | 01/01/1991 | ||||
Data de entrada: | 19/11/1974 | ||||
Data de revisão: | 30/06/2005 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes
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2-Isopropylmalate Synthase
- Conceito preferido
Identificador do conceito |
M0023192 |
Nota de escopo | An enzyme that catalyzes the first step in the biosynthetic pathway to LEUCINE, forming isopropyl malate from acetyl-CoA and alpha-ketoisovaleric acid. This enzyme was formerly listed as EC 4.1.3.12. |
Termo preferido | 2-Isopropylmalate Synthase |
Termo(s) alternativo(s) |
2 Isopropylmalate Synthase Synthase, 2-Isopropylmalate Synthase, alpha-Isopropylmalate alpha Isopropylmalate Synthase alpha-Isopropylmalate Synthase |
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