Pesquisa
Descritor em português: Leucil Aminopeptidase
Descritor em inglês: Leucyl Aminopeptidase
Descritor em espanhol: Leucil Aminopeptidasa
Descritor leucil aminopeptidasa
Termo(s) alternativo(s) citosol aminopeptidasa
leucil beta-naftilamidasa
leucina aminopeptidasa
Nota de escopo: Enzima de la clase de las hidrolasas que contiene zinc y cataliza la separación del aminoácido N-terminal de la mayoría de los L-péptidos, particularmente aquellos con residuos de leucina N-terminal, pero los que contienen residuos N-terminales de lisina o arginina. Esto tiene lugar en el citosol celular y existe elevada actividad en el duodeno, hígado y riñón. EC 3.4.11.1.
Descritor em francês: Leucyl Aminopeptidase
Termo(s) alternativo(s): Aminopeptidase, Cytosol
Aminopeptidase, Leucine
Aminopeptidase, Leucyl
Aminopeptidase, Methoxyleucine
Aminopeptidase, Zinc-Manganese-Leucine
Cytosol Aminopeptidase
L-Leucylnaphthylamidase
Leucine Aminopeptidase
Methoxyleucine Aminopeptidase
Peptidase S
Zinc Manganese Leucine Aminopeptidase
Zinc-Manganese-Leucine Aminopeptidase
Código(s) hierárquico(s): D08.811.277.656.350.100.511
D08.811.277.656.350.555.700
D08.811.277.656.675.555.700
Identificador Único RDF: https://id.nlm.nih.gov/mesh/D007931
Nota de escopo: A zinc containing enzyme of the hydrolase class that catalyzes the removal of the N-terminal amino acid from most L-peptides, particularly those with N-terminal leucine residues but not those with N-terminal lysine or arginine residues. This occurs in tissue cell cytosol, with high activity in the duodenum, liver, and kidney. The activity of this enzyme is commonly assayed using a leucine arylamide chromogenic substrate such as leucyl beta-naphthylamide.
Qualificadores permitidos: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Número de registro: EC 3.4.11.1
Nota MeSH pública: 1999; see LEUCINE AMINOPEPTIDASE 1965-1998; PEPTIDASE S was indexed under AMINOPEPTIDASES 1979-1998; for LEUCYL-BETA-NAPTHYLAMIDASE see LEUCYL-BETA-NAPTHYLAMIDASE 1991-2009
Nota histórica: 1999(1965)
Identificador DeCS: 8109
ID do descritor: D007931
Documentos indexados na Biblioteca Virtual em Saúde (BVS): Clique aqui para acessar os documentos da BVS
Data de estabelecimento: 01/01/1965
Data de entrada: 01/01/1999
Data de revisão: 28/06/2016
Leucyl Aminopeptidase - Conceito preferido
Identificador do conceito M0012373
Nota de escopo A zinc containing enzyme of the hydrolase class that catalyzes the removal of the N-terminal amino acid from most L-peptides, particularly those with N-terminal leucine residues but not those with N-terminal lysine or arginine residues. This occurs in tissue cell cytosol, with high activity in the duodenum, liver, and kidney. The activity of this enzyme is commonly assayed using a leucine arylamide chromogenic substrate such as leucyl beta-naphthylamide.
Termo preferido Leucyl Aminopeptidase
Termo(s) alternativo(s) Aminopeptidase, Cytosol
Aminopeptidase, Leucine
Aminopeptidase, Leucyl
Aminopeptidase, Zinc-Manganese-Leucine
Cytosol Aminopeptidase
L-Leucylnaphthylamidase
Leucine Aminopeptidase
Peptidase S
Zinc Manganese Leucine Aminopeptidase
Zinc-Manganese-Leucine Aminopeptidase
Methoxyleucine Aminopeptidase - Mais específico
Identificador do conceito M0012374
Termo preferido Methoxyleucine Aminopeptidase
Termo(s) alternativo(s) Aminopeptidase, Methoxyleucine



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