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Descriptor English: Clofazimine
Descriptor Spanish: Clofazimina
Descriptor clofacimina
Scope note: Colorante liposoluble de riminofenazina utilizado en el tratamiento de la lepra. En investigación, se ha utilizado combinado con otros fármacos antimicobacterianos para tratar infecciones por Mycobacterium avium en pacientes con SIDA. La clofacimina tambien tiene marcados efectos anti-inflamatorios y se administra para controlar la reacción leprosa, eritema nodoso leproso. (de AMA Drug Evaluations Annual, 1993, p1619)
Descriptor Portuguese: Clofazimina
Descriptor French: Clofazimine
Entry term(s): B 663
B-663
B663
G 30,320
G-30,320
G30,320
Lamprene
N,5-Bis(4-chlorophenyl)-3,5-dihydro-3-((1-methylethyl)imino)-2-phenazinamine
Tree number(s): D03.633.300.704.353
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D002991
Scope note: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Anti-Inflammatory Agents
Leprostatic Agents
Registry Number: D959AE5USF
CAS Type 1 Name: 2-Phenazinamine, N,5-bis(4-chlorophenyl)-3,5-dihydro-3-((1-methylethyl)imino)-
Public MeSH Note: 74
History Note: 74
DeCS ID: 3015
Unique ID: D002991
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1974/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/05/28
Clofazimine - Preferred
Concept UI M0004579
Scope note A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
Preferred term Clofazimine
Entry term(s) N,5-Bis(4-chlorophenyl)-3,5-dihydro-3-((1-methylethyl)imino)-2-phenazinamine
Lamprene - Narrower
Concept UI M0004580
Preferred term Lamprene
B-663 - Narrower
Concept UI M0354093
Preferred term B-663
Entry term(s) B 663
B663
G-30,320 - Narrower
Concept UI M0354094
Preferred term G-30,320
Entry term(s) G 30,320
G30,320



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